Trait: diabetes mellitus

Experimental Factor Ontology (EFO) Information
Identifier EFO_0000400
Description A metabolic disorder characterized by abnormally high blood sugar levels due to diminished production of insulin or insulin resistance/desensitization. [NCIT: P378]
Trait categories
Digestive system disorder
Metabolic disorder
Synonyms 9 synonyms
  • DM
  • DM - Diabetes mellitus
  • Diabetes
  • Diabetes NOS
  • Diabetes mellitus (disorder)
  • Diabetes mellitus, NOS
  • diabetes
  • diabetes mellitus
  • diabetes mellitus (disease)
Mapped terms 22 mapped terms
  • DOID:9351
  • HP:0000819
  • ICD10:E13
  • ICD10:E14
  • ICD10CM:E08-E13
  • ICD9:250
  • MEDGEN:8350
  • MESH:D003920
  • MONDO:0005015
  • MeSH:D003920
  • MedDRA:10012601
  • MedDRA:10012624
  • MedDRA:10012625
  • NANDO:2100157
  • NANDO:2100158
  • NCIT:C2985
  • NCIt:C2985
  • OMIM:612227
  • SCTID:73211009
  • SNOMEDCT:73211009
  • UMLS:C0011849
  • icd11.foundation:465177735
Child trait(s) 3 child traits

Associated Polygenic Score(s)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Note: This table shows all PGS for "diabetes mellitus" and any child terms of this trait in the EFO hierarchy by default.
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
Scoring File (FTP Link)
PGS000014
(GPS_T2D)
PGP000006 |
Khera AV et al. Nat Genet (2018)
Type 2 diabetes (T2D) type 2 diabetes mellitus 6,917,436
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000014/ScoringFiles/PGS000014.txt.gz - Check Terms/Licenses
PGS000020
(dGRS1000)
PGP000010 |
Läll K et al. Genet Med (2016)
Type 2 diabetes (T2D) type 2 diabetes mellitus 7,502
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000020/ScoringFiles/PGS000020.txt.gz
PGS000021
(GRS1)
PGP000011 |
Oram RA et al. Diabetes Care (2015)
Type 1 diabetes (T1D) type 1 diabetes mellitus 33
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000021/ScoringFiles/PGS000021.txt.gz
PGS000022
(T1D_GRS)
PGP000012 |
Perry DJ et al. Sci Rep (2018)
Type 1 diabetes (T1D) type 1 diabetes mellitus 37
-
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000022/ScoringFiles/PGS000022.txt.gz
PGS000023
(AA_GRS)
PGP000013 |
Onengut-Gumuscu S et al. Diabetes Care (2019)
Type 1 diabetes (T1D) type 1 diabetes mellitus 7
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000023/ScoringFiles/PGS000023.txt.gz
PGS000024
(GRS2)
PGP000014 |
Sharp SA et al. Diabetes Care (2019)
Type 1 diabetes (T1D) type 1 diabetes mellitus 85
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000024/ScoringFiles/PGS000024.txt.gz
PGS000031
(GRSt)
PGP000020 |
Vassy JL et al. Diabetes (2014)
Type 2 diabetes (T2D) type 2 diabetes mellitus 62
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000031/ScoringFiles/PGS000031.txt.gz
PGS000032
(GRSB)
PGP000020 |
Vassy JL et al. Diabetes (2014)
Type 2 diabetes (based on SNPs involved in β-cell function) type 2 diabetes mellitus 20
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000032/ScoringFiles/PGS000032.txt.gz
PGS000033
(GRSIR)
PGP000020 |
Vassy JL et al. Diabetes (2014)
Type 2 diabetes (based on SNPs involved in insulin resistance) type 2 diabetes mellitus 10
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000033/ScoringFiles/PGS000033.txt.gz
PGS000036
(gePS_T2D)
PGP000023 |
Mahajan A et al. Nat Genet (2018)
Type 2 diabetes (T2D) type 2 diabetes mellitus 171,249
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000036/ScoringFiles/PGS000036.txt.gz
PGS000125
(Qi_T2D_2017)
PGP000062 |
Qi Q et al. Diabetes (2017)
Type 2 diabetes (T2D) type 2 diabetes mellitus 80
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000125/ScoringFiles/PGS000125.txt.gz
PGS000330
(PRS_T2D)
PGP000100 |
Mars N et al. Nat Med (2020)
Type 2 diabetes (T2D) type 2 diabetes mellitus 6,437,380
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000330/ScoringFiles/PGS000330.txt.gz
PGS000712
(T2D_HbA1c_39)
PGP000128 |
Sinnott-Armstrong N et al. Nat Genet (2021)
T2D (cases vs HbA1c filtered controls) type 2 diabetes mellitus 183,695
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000712/ScoringFiles/PGS000712.txt.gz - Check Terms/Licenses
PGS000713
(T2D)
PGP000128 |
Sinnott-Armstrong N et al. Nat Genet (2021)
Type 2 diabetes (T2D) type 2 diabetes mellitus 183,830
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000713/ScoringFiles/PGS000713.txt.gz - Check Terms/Licenses
PGS000729
(T2D_PGS)
PGP000137 |
Ritchie SC et al. Nat Metab (2021)
Type 2 diabetes (T2D) type 2 diabetes mellitus 2,017,388
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000729/ScoringFiles/PGS000729.txt.gz
PGS000804
(GRS582_T2Dmulti)
PGP000193 |
Polfus LM et al. HGG Adv (2021)
Type 2 diabetes (T2D) type 2 diabetes mellitus 582
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000804/ScoringFiles/PGS000804.txt.gz - Check Terms/Licenses
PGS000805
(GRS582_T2Deur)
PGP000193 |
Polfus LM et al. HGG Adv (2021)
Type 2 diabetes (T2D) type 2 diabetes mellitus 582
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000805/ScoringFiles/PGS000805.txt.gz - Check Terms/Licenses
PGS000806
(GRS582_T2Dafr)
PGP000193 |
Polfus LM et al. HGG Adv (2021)
Type 2 diabetes (T2D) type 2 diabetes mellitus 582
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000806/ScoringFiles/PGS000806.txt.gz - Check Terms/Licenses
PGS000807
(GRS582_T2Dasn)
PGP000193 |
Polfus LM et al. HGG Adv (2021)
Type 2 diabetes (T2D) type 2 diabetes mellitus 582
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000807/ScoringFiles/PGS000807.txt.gz - Check Terms/Licenses
PGS000808
(GRS582_T2Dhis)
PGP000193 |
Polfus LM et al. HGG Adv (2021)
Type 2 diabetes (T2D) type 2 diabetes mellitus 582
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000808/ScoringFiles/PGS000808.txt.gz - Check Terms/Licenses
PGS000832
(T2D-GRS)
PGP000211 |
Aly DM et al. Nat Genet (2021)
Type 2 diabetes (T2D) type 2 diabetes mellitus 384
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000832/ScoringFiles/PGS000832.txt.gz
PGS000833
(T1D)
PGP000211 |
Aly DM et al. Nat Genet (2021)
Type 1 diabetes (T1D) type 1 diabetes mellitus 66
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000833/ScoringFiles/PGS000833.txt.gz
PGS000848
(T2D_Adiposity)
PGP000211 |
Aly DM et al. Nat Genet (2021)
Type 2 diabetes (based on SNPs associated with adiposity) type 2 diabetes mellitus 6
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000848/ScoringFiles/PGS000848.txt.gz
PGS000849
(T2D_Impaired_Lipids)
PGP000211 |
Aly DM et al. Nat Genet (2021)
Type 2 diabetes (based on SNPs associated with impaired lipids) type 2 diabetes mellitus 3
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000849/ScoringFiles/PGS000849.txt.gz
PGS000850
(T2D_Insulin_Action)
PGP000211 |
Aly DM et al. Nat Genet (2021)
Type 2 diabetes (based on SNPs associated with insulin action) type 2 diabetes mellitus 16
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000850/ScoringFiles/PGS000850.txt.gz
PGS000851
(T2D_Insulin_Action_Secretion)
PGP000211 |
Aly DM et al. Nat Genet (2021)
Type 2 diabetes (based on SNPs associated with insulin action/secretion) type 2 diabetes mellitus 37
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000851/ScoringFiles/PGS000851.txt.gz
PGS000852
(T2D_Insulin_Secretion_1)
PGP000211 |
Aly DM et al. Nat Genet (2021)
Type 2 diabetes (based on SNPs associated with insulin secretion) type 2 diabetes mellitus 8
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000852/ScoringFiles/PGS000852.txt.gz
PGS000853
(T2D_Insulin_Secretion_2)
PGP000211 |
Aly DM et al. Nat Genet (2021)
Type 2 diabetes (based on SNPs associated with insulin secretion) type 2 diabetes mellitus 21
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000853/ScoringFiles/PGS000853.txt.gz
PGS000854
(T2D_BetaCell)
PGP000211 |
Aly DM et al. Nat Genet (2021)
Type 2 diabetes (based on SNPs associated with beta cell function) type 2 diabetes mellitus 27
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000854/ScoringFiles/PGS000854.txt.gz
PGS000855
(T2D_Lipodystrophy)
PGP000211 |
Aly DM et al. Nat Genet (2021)
Type 2 diabetes (based on SNPs associated with lipodystrophy) type 2 diabetes mellitus 18
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000855/ScoringFiles/PGS000855.txt.gz
PGS000856
(T2D_LiverLipids)
PGP000211 |
Aly DM et al. Nat Genet (2021)
Type 2 diabetes (based on SNPs associated with liver lipids) type 2 diabetes mellitus 3
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000856/ScoringFiles/PGS000856.txt.gz
PGS000857
(T2D_Obesity)
PGP000211 |
Aly DM et al. Nat Genet (2021)
Type 2 diabetes (based on SNPs associated with obesity) type 2 diabetes mellitus 4
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000857/ScoringFiles/PGS000857.txt.gz
PGS000858
(T2D_Proinsulin)
PGP000211 |
Aly DM et al. Nat Genet (2021)
Type 2 diabetes (based on SNPs associated with proinsulin levels) type 2 diabetes mellitus 6
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000858/ScoringFiles/PGS000858.txt.gz
PGS000864
(T2D-gPRS)
PGP000211 |
Aly DM et al. Nat Genet (2021)
Type 2 diabetes (T2D) type 2 diabetes mellitus 389,243
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000864/ScoringFiles/PGS000864.txt.gz
PGS000868
(T2D_221)
PGP000214 |
Aksit MA et al. J Clin Endocrinol Metab (2020)
Type 2 diabetes (T2D) type 2 diabetes mellitus 221
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000868/ScoringFiles/PGS000868.txt.gz
PGS000869
(T1D_48)
PGP000214 |
Aksit MA et al. J Clin Endocrinol Metab (2020)
Type 1 diabetes (T1D) type 1 diabetes mellitus 48
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000869/ScoringFiles/PGS000869.txt.gz
PGS001294
(GBE_HC649)
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Non-insulin-dependent diabetes (time-to-event) type 2 diabetes mellitus 3,496
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001294/ScoringFiles/PGS001294.txt.gz
PGS001295
(GBE_HC165)
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Type 2 diabetes (T2D) type 2 diabetes mellitus 385
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001295/ScoringFiles/PGS001295.txt.gz
PGS001296
(GBE_HC648)
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Insulin-dependent diabetes mellitus (time-to-event) type 1 diabetes mellitus 356
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001296/ScoringFiles/PGS001296.txt.gz
PGS001297
(GBE_HC337)
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Type 1 diabetes (T1D) type 1 diabetes mellitus 69
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001297/ScoringFiles/PGS001297.txt.gz
PGS001327
(GBE_HC221)
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Diabetes diabetes mellitus 4,053
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001327/ScoringFiles/PGS001327.txt.gz
PGS001329
(GBE_HC652)
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Unspecified diabetes mellitus (time-to-event) diabetes mellitus 2,270
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001329/ScoringFiles/PGS001329.txt.gz
PGS001357
(T2D_AnnoPred_PRS)
PGP000252 |
Ye Y et al. Circ Genom Precis Med (2021)
Type 2 diabetes (T2D) type 2 diabetes mellitus 2,996,761
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001357/ScoringFiles/PGS001357.txt.gz
PGS001371
(GBE_INI2976)
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Age diabetes diagnosed diabetes mellitus,
age at diagnosis
26
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001371/ScoringFiles/PGS001371.txt.gz
PGS001781
(T2D_PRSCS)
PGP000261 |
Tamlander M et al. Commun Biol (2022)
Type 2 diabetes (T2D) type 2 diabetes mellitus 1,091,673
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001781/ScoringFiles/PGS001781.txt.gz
PGS001817
(portability-PLR_250.1)
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Type 1 diabetes (T1D) type 1 diabetes mellitus 825
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001817/ScoringFiles/PGS001817.txt.gz
PGS001818
(portability-PLR_250.2)
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Type 2 diabetes (T2D) type 2 diabetes mellitus 30,745
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001818/ScoringFiles/PGS001818.txt.gz
PGS002025
(portability-ldpred2_250.1)
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Type 1 diabetes (T1D) type 1 diabetes mellitus 106,800
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002025/ScoringFiles/PGS002025.txt.gz
PGS002026
(portability-ldpred2_250.2)
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Type 2 diabetes (T2D) type 2 diabetes mellitus 830,783
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002026/ScoringFiles/PGS002026.txt.gz
PGS002243
(ldpred_t2d)
PGP000271 |
Mars N et al. Cell Genom (2022)
Type 2 diabetes (T2D) type 2 diabetes mellitus 6,431,973
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002243/ScoringFiles/PGS002243.txt.gz
PGS002256
(GRS4_GDM)
PGP000282 |
Wu Q et al. Diabetol Metab Syndr (2022)
Gestational diabetes mellitus in early pregnancy gestational diabetes 4
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002256/ScoringFiles/PGS002256.txt.gz
PGS002277
(pPS_Insulin_secretion_1)
PGP000305 |
Siddiqui MK et al. Diabetologia (2022)
Type 2 diabetes (based on SNPs associated with insulin secretion) type 2 diabetes mellitus 8
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002277/ScoringFiles/PGS002277.txt.gz
PGS002308
(PRScsx_T2D)
PGP000331 |
Ge T et al. Genome Med (2022)
Type 2 diabetes (T2D) type 2 diabetes mellitus 1,259,754
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002308/ScoringFiles/PGS002308.txt.gz
PGS002321
(disease_DIABETES_ANY_DIAGNOSED.BOLT-LMM)
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Diabetes (any type) diabetes mellitus 1,109,311
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002321/ScoringFiles/PGS002321.txt.gz
PGS002324
(disease_ENDOCRINE_DIABETES.BOLT-LMM)
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Endocrine and diabetes diseases diabetes mellitus,
endocrine system disease
1,109,311
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002324/ScoringFiles/PGS002324.txt.gz
PGS002354
(disease_T2D.BOLT-LMM)
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Type 2 diabetes (T2D) type 2 diabetes mellitus 1,109,311
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002354/ScoringFiles/PGS002354.txt.gz
PGS002379
(disease_T2D.BOLT-LMM-BBJ)
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Type 2 diabetes (T2D) type 2 diabetes mellitus 920,930
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002379/ScoringFiles/PGS002379.txt.gz
PGS002393
(disease_DIABETES_ANY_DIAGNOSED.P+T.0.0001)
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Diabetes (any type) diabetes mellitus 3,813
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002393/ScoringFiles/PGS002393.txt.gz
PGS002396
(disease_ENDOCRINE_DIABETES.P+T.0.0001)
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Endocrine and diabetes diseases diabetes mellitus,
endocrine system disease
3,681
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002396/ScoringFiles/PGS002396.txt.gz
PGS002426
(disease_T2D.P+T.0.0001)
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Type 2 diabetes (T2D) type 2 diabetes mellitus 3,947
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002426/ScoringFiles/PGS002426.txt.gz
PGS002442
(disease_DIABETES_ANY_DIAGNOSED.P+T.0.001)
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Diabetes (any type) diabetes mellitus 15,915
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002442/ScoringFiles/PGS002442.txt.gz
PGS002445
(disease_ENDOCRINE_DIABETES.P+T.0.001)
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Endocrine and diabetes diseases diabetes mellitus,
endocrine system disease
15,629
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002445/ScoringFiles/PGS002445.txt.gz
PGS002475
(disease_T2D.P+T.0.001)
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Type 2 diabetes (T2D) type 2 diabetes mellitus 16,275
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002475/ScoringFiles/PGS002475.txt.gz
PGS002491
(disease_DIABETES_ANY_DIAGNOSED.P+T.0.01)
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Diabetes (any type) diabetes mellitus 95,066
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002491/ScoringFiles/PGS002491.txt.gz
PGS002494
(disease_ENDOCRINE_DIABETES.P+T.0.01)
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Endocrine and diabetes diseases diabetes mellitus,
endocrine system disease
93,293
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002494/ScoringFiles/PGS002494.txt.gz
PGS002524
(disease_T2D.P+T.0.01)
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Type 2 diabetes (T2D) type 2 diabetes mellitus 95,287
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002524/ScoringFiles/PGS002524.txt.gz
PGS002540
(disease_DIABETES_ANY_DIAGNOSED.P+T.1e-06)
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Diabetes (any type) diabetes mellitus 598
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002540/ScoringFiles/PGS002540.txt.gz
PGS002543
(disease_ENDOCRINE_DIABETES.P+T.1e-06)
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Endocrine and diabetes diseases diabetes mellitus,
endocrine system disease
528
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002543/ScoringFiles/PGS002543.txt.gz
PGS002573
(disease_T2D.P+T.1e-06)
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Type 2 diabetes (T2D) type 2 diabetes mellitus 673
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002573/ScoringFiles/PGS002573.txt.gz
PGS002589
(disease_DIABETES_ANY_DIAGNOSED.P+T.5e-08)
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Diabetes (any type) diabetes mellitus 267
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002589/ScoringFiles/PGS002589.txt.gz
PGS002592
(disease_ENDOCRINE_DIABETES.P+T.5e-08)
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Endocrine and diabetes diseases diabetes mellitus,
endocrine system disease
187
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002592/ScoringFiles/PGS002592.txt.gz
PGS002622
(disease_T2D.P+T.5e-08)
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Type 2 diabetes (T2D) type 2 diabetes mellitus 293
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002622/ScoringFiles/PGS002622.txt.gz
PGS002638
(disease_DIABETES_ANY_DIAGNOSED.PolyFun-pred)
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Diabetes (any type) diabetes mellitus 247,386
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002638/ScoringFiles/PGS002638.txt.gz
PGS002641
(disease_ENDOCRINE_DIABETES.PolyFun-pred)
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Endocrine and diabetes diseases diabetes mellitus,
endocrine system disease
256,678
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002641/ScoringFiles/PGS002641.txt.gz
PGS002671
(disease_T2D.PolyFun-pred)
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Type 2 diabetes (T2D) type 2 diabetes mellitus 258,382
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002671/ScoringFiles/PGS002671.txt.gz
PGS002687
(disease_DIABETES_ANY_DIAGNOSED.SBayesR)
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Diabetes (any type) diabetes mellitus 923,080
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002687/ScoringFiles/PGS002687.txt.gz
PGS002690
(disease_ENDOCRINE_DIABETES.SBayesR)
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Endocrine and diabetes diseases diabetes mellitus,
endocrine system disease
905,637
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002690/ScoringFiles/PGS002690.txt.gz
PGS002720
(disease_T2D.SBayesR)
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Type 2 diabetes (T2D) type 2 diabetes mellitus 911,809
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002720/ScoringFiles/PGS002720.txt.gz
PGS002733
(GRS17_T2D)
PGP000342 |
Pezzilli S et al. Diabetes Metab (2022)
Type 2 diabetes (T2D) type 2 diabetes mellitus 17
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002733/ScoringFiles/PGS002733.txt.gz
PGS002771
(Type_2_diabetes_prscs)
PGP000364 |
Mars N et al. Am J Hum Genet (2022)
Type 2 diabetes (T2D) type 2 diabetes mellitus 1,091,608
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002771/ScoringFiles/PGS002771.txt.gz
PGS002779
(GTG_T2D_maxCT)
PGP000365 |
Wong CK et al. PLoS One (2022)
Incident type 2 diabetes type 2 diabetes mellitus 46,353
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002779/ScoringFiles/PGS002779.txt.gz - Check Terms/Licenses
PGS002780
(GTG_T2D_SCT)
PGP000365 |
Wong CK et al. PLoS One (2022)
Incident type 2 diabetes type 2 diabetes mellitus 419,209
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002780/ScoringFiles/PGS002780.txt.gz - Check Terms/Licenses
PGS003089
(ExPRSweb_T2D_2443_LASSOSUM_MGI_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Type 2 diabetes (T2D) type 2 diabetes mellitus 488,969
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003089/ScoringFiles/PGS003089.txt.gz
PGS003090
(ExPRSweb_T2D_2443_PT_MGI_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Type 2 diabetes (T2D) type 2 diabetes mellitus 1,888
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003090/ScoringFiles/PGS003090.txt.gz
PGS003091
(ExPRSweb_T2D_2443_PLINK_MGI_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Type 2 diabetes (T2D) type 2 diabetes mellitus 2,707
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003091/ScoringFiles/PGS003091.txt.gz
PGS003092
(ExPRSweb_T2D_2443_DBSLMM_MGI_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Type 2 diabetes (T2D) type 2 diabetes mellitus 10,304,000
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003092/ScoringFiles/PGS003092.txt.gz
PGS003093
(ExPRSweb_T2D_2443_PRSCS_MGI_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Type 2 diabetes (T2D) type 2 diabetes mellitus 1,113,832
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003093/ScoringFiles/PGS003093.txt.gz
PGS003094
(ExPRSweb_T2D_29358691-GCST005413_LASSOSUM_MGI_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Type 2 diabetes (T2D) type 2 diabetes mellitus 266,890
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003094/ScoringFiles/PGS003094.txt.gz
PGS003095
(ExPRSweb_T2D_29358691-GCST005413_PT_MGI_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Type 2 diabetes (T2D) type 2 diabetes mellitus 45
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003095/ScoringFiles/PGS003095.txt.gz
PGS003096
(ExPRSweb_T2D_29358691-GCST005413_PLINK_MGI_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Type 2 diabetes (T2D) type 2 diabetes mellitus 46
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003096/ScoringFiles/PGS003096.txt.gz
PGS003097
(ExPRSweb_T2D_29358691-GCST005413_DBSLMM_MGI_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Type 2 diabetes (T2D) type 2 diabetes mellitus 229
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003097/ScoringFiles/PGS003097.txt.gz
PGS003098
(ExPRSweb_T2D_29358691-GCST005413_PRSCS_MGI_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Type 2 diabetes (T2D) type 2 diabetes mellitus 1,116,101
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003098/ScoringFiles/PGS003098.txt.gz
PGS003099
(ExPRSweb_T2D_30054458-GCST006867_LASSOSUM_MGI_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Type 2 diabetes (T2D) type 2 diabetes mellitus 555,512
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003099/ScoringFiles/PGS003099.txt.gz
PGS003100
(ExPRSweb_T2D_30054458-GCST006867_PT_MGI_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Type 2 diabetes (T2D) type 2 diabetes mellitus 5,693
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003100/ScoringFiles/PGS003100.txt.gz
PGS003101
(ExPRSweb_T2D_30054458-GCST006867_PLINK_MGI_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Type 2 diabetes (T2D) type 2 diabetes mellitus 5,693
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003101/ScoringFiles/PGS003101.txt.gz
PGS003102
(ExPRSweb_T2D_30054458-GCST006867_DBSLMM_MGI_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Type 2 diabetes (T2D) type 2 diabetes mellitus 5,052,574
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003102/ScoringFiles/PGS003102.txt.gz
PGS003103
(ExPRSweb_T2D_30054458-GCST006867_PRSCS_MGI_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Type 2 diabetes (T2D) type 2 diabetes mellitus 945,820
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003103/ScoringFiles/PGS003103.txt.gz
PGS003104
(ExPRSweb_T2D_METAANALYSIS-DIAGRAM_LASSOSUM_MGI_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Type 2 diabetes (T2D) type 2 diabetes mellitus 374,510
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003104/ScoringFiles/PGS003104.txt.gz
PGS003105
(ExPRSweb_T2D_METAANALYSIS-DIAGRAM_PT_MGI_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Type 2 diabetes (T2D) type 2 diabetes mellitus 187
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003105/ScoringFiles/PGS003105.txt.gz
PGS003106
(ExPRSweb_T2D_METAANALYSIS-DIAGRAM_PLINK_MGI_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Type 2 diabetes (T2D) type 2 diabetes mellitus 187
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003106/ScoringFiles/PGS003106.txt.gz
PGS003107
(ExPRSweb_T2D_METAANALYSIS-DIAGRAM_DBSLMM_MGI_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Type 2 diabetes (T2D) type 2 diabetes mellitus 995
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003107/ScoringFiles/PGS003107.txt.gz
PGS003108
(ExPRSweb_T2D_METAANALYSIS-DIAGRAM_PRSCS_MGI_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Type 2 diabetes (T2D) type 2 diabetes mellitus 1,118,480
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003108/ScoringFiles/PGS003108.txt.gz
PGS003109
(ExPRSweb_T2D_29358691-GCST005413_LASSOSUM_UKB_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Type 2 diabetes (T2D) type 2 diabetes mellitus 311,565
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003109/ScoringFiles/PGS003109.txt.gz
PGS003110
(ExPRSweb_T2D_29358691-GCST005413_PT_UKB_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Type 2 diabetes (T2D) type 2 diabetes mellitus 118
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003110/ScoringFiles/PGS003110.txt.gz
PGS003111
(ExPRSweb_T2D_29358691-GCST005413_PLINK_UKB_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Type 2 diabetes (T2D) type 2 diabetes mellitus 143
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003111/ScoringFiles/PGS003111.txt.gz
PGS003112
(ExPRSweb_T2D_29358691-GCST005413_DBSLMM_UKB_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Type 2 diabetes (T2D) type 2 diabetes mellitus 222
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003112/ScoringFiles/PGS003112.txt.gz
PGS003113
(ExPRSweb_T2D_29358691-GCST005413_PRSCS_UKB_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Type 2 diabetes (T2D) type 2 diabetes mellitus 1,117,087
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003113/ScoringFiles/PGS003113.txt.gz
PGS003114
(ExPRSweb_T2D_30054458-GCST006867_LASSOSUM_UKB_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Type 2 diabetes (T2D) type 2 diabetes mellitus 555,528
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003114/ScoringFiles/PGS003114.txt.gz
PGS003115
(ExPRSweb_T2D_30054458-GCST006867_PT_UKB_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Type 2 diabetes (T2D) type 2 diabetes mellitus 31,462
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003115/ScoringFiles/PGS003115.txt.gz
PGS003116
(ExPRSweb_T2D_30054458-GCST006867_PLINK_UKB_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Type 2 diabetes (T2D) type 2 diabetes mellitus 31,462
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003116/ScoringFiles/PGS003116.txt.gz
PGS003117
(ExPRSweb_T2D_30054458-GCST006867_DBSLMM_UKB_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Type 2 diabetes (T2D) type 2 diabetes mellitus 5,052,993
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003117/ScoringFiles/PGS003117.txt.gz
PGS003118
(ExPRSweb_T2D_30054458-GCST006867_PRSCS_UKB_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Type 2 diabetes (T2D) type 2 diabetes mellitus 945,921
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003118/ScoringFiles/PGS003118.txt.gz
PGS003119
(ExPRSweb_T2D_METAANALYSIS-DIAGRAM_LASSOSUM_UKB_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Type 2 diabetes (T2D) type 2 diabetes mellitus 407,553
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003119/ScoringFiles/PGS003119.txt.gz
PGS003120
(ExPRSweb_T2D_METAANALYSIS-DIAGRAM_PT_UKB_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Type 2 diabetes (T2D) type 2 diabetes mellitus 193
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003120/ScoringFiles/PGS003120.txt.gz
PGS003121
(ExPRSweb_T2D_METAANALYSIS-DIAGRAM_PLINK_UKB_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Type 2 diabetes (T2D) type 2 diabetes mellitus 193
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003121/ScoringFiles/PGS003121.txt.gz
PGS003122
(ExPRSweb_T2D_METAANALYSIS-DIAGRAM_DBSLMM_UKB_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Type 2 diabetes (T2D) type 2 diabetes mellitus 264
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003122/ScoringFiles/PGS003122.txt.gz
PGS003123
(ExPRSweb_T2D_METAANALYSIS-DIAGRAM_PRSCS_UKB_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Type 2 diabetes (T2D) type 2 diabetes mellitus 1,119,522
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003123/ScoringFiles/PGS003123.txt.gz
PGS003353
(GRS_T2D)
PGP000405 |
Kim YJ et al. Nat Commun (2022)
Type 2 diabetes (T2D) type 2 diabetes mellitus 287
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003353/ScoringFiles/PGS003353.txt.gz
PGS003402
(PRS_T2D)
PGP000419 |
Lamri A et al. Elife (2022)
Type 2 diabetes (T2D) type 2 diabetes mellitus 6,838
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003402/ScoringFiles/PGS003402.txt.gz
PGS003443
(PRScsx_T2D_LAT_EURweights)
PGP000445 |
Huerta-Chagoya A et al. Diabetologia (2023)
Type 2 diabetes (T2D) type 2 diabetes mellitus 1,092,496
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003443/ScoringFiles/PGS003443.txt.gz
PGS003444
(PRScsx_T2D_LAT_EASweights)
PGP000445 |
Huerta-Chagoya A et al. Diabetologia (2023)
Type 2 diabetes (T2D) type 2 diabetes mellitus 1,001,579
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003444/ScoringFiles/PGS003444.txt.gz
PGS003445
(PRScsx_T2D_LAT_LATweights)
PGP000445 |
Huerta-Chagoya A et al. Diabetologia (2023)
Type 2 diabetes (T2D) type 2 diabetes mellitus 1,149,210
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003445/ScoringFiles/PGS003445.txt.gz
PGS003728
(PS_T2D_183-AGEN)
PGP000469 |
Wedekind LE et al. Diabetologia (2023)
Type 2 diabetes (T2D) type 2 diabetes mellitus 183
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003728/ScoringFiles/PGS003728.txt.gz
PGS003729
(PS_T2D_293-DIAGRAM)
PGP000469 |
Wedekind LE et al. Diabetologia (2023)
Type 2 diabetes (T2D) type 2 diabetes mellitus 293
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003729/ScoringFiles/PGS003729.txt.gz
PGS003730
(PS_T2D_287-DIAMANTE)
PGP000469 |
Wedekind LE et al. Diabetologia (2023)
Type 2 diabetes (T2D) type 2 diabetes mellitus 287
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003730/ScoringFiles/PGS003730.txt.gz
PGS003731
(PS_T2D_282-SAS-DIAMANTE)
PGP000469 |
Wedekind LE et al. Diabetologia (2023)
Type 2 diabetes (T2D) type 2 diabetes mellitus 282
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003731/ScoringFiles/PGS003731.txt.gz
PGS003732
(PS_T2D_287-HIS-DIAMANTE)
PGP000469 |
Wedekind LE et al. Diabetologia (2023)
Type 2 diabetes (T2D) type 2 diabetes mellitus 287
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003732/ScoringFiles/PGS003732.txt.gz
PGS003733
(PS_T2D_287-EUR-DIAMANTE)
PGP000469 |
Wedekind LE et al. Diabetologia (2023)
Type 2 diabetes (T2D) type 2 diabetes mellitus 287
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003733/ScoringFiles/PGS003733.txt.gz
PGS003734
(PS_T2D_280-EAS-DIAMANTE)
PGP000469 |
Wedekind LE et al. Diabetologia (2023)
Type 2 diabetes (T2D) type 2 diabetes mellitus 280
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003734/ScoringFiles/PGS003734.txt.gz
PGS003735
(PS_T2D_276-AFR-DIAMANTE)
PGP000469 |
Wedekind LE et al. Diabetologia (2023)
Type 2 diabetes (T2D) type 2 diabetes mellitus 276
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003735/ScoringFiles/PGS003735.txt.gz
PGS003749
(ModelT1D_under25)
PGP000472 |
Shoaib M et al. Genet Epidemiol (2023)
Type 1 diabetes (T1D) type 1 diabetes mellitus 6,612
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003749/ScoringFiles/PGS003749.txt.gz
PGS003750
(ModelT1D)
PGP000472 |
Shoaib M et al. Genet Epidemiol (2023)
Type 1 diabetes (T1D) type 1 diabetes mellitus 7,835
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003750/ScoringFiles/PGS003750.txt.gz
PGS003751
(ModelT2D_over45)
PGP000472 |
Shoaib M et al. Genet Epidemiol (2023)
Type 2 diabetes (T2D) type 2 diabetes mellitus 354
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003751/ScoringFiles/PGS003751.txt.gz
PGS003752
(ModelT2D)
PGP000472 |
Shoaib M et al. Genet Epidemiol (2023)
Type 2 diabetes (T2D) type 2 diabetes mellitus 333
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003752/ScoringFiles/PGS003752.txt.gz
PGS003867
(T2D_PRScs_ARB)
PGP000501 |
Shim I et al. Nature Communications (2023)
Type 2 diabetes (T2D) type 2 diabetes mellitus 1,068,166
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003867/ScoringFiles/PGS003867.txt.gz
PGS003982
(dbslmm.auto.GCST004773.T2D)
PGP000517 |
Monti R et al. Am J Hum Genet (2024)
Type 2 diabetes (T2D) type 2 diabetes mellitus 1,071,764
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003982/ScoringFiles/PGS003982.txt.gz
PGS003993
(dbslmm.auto.GCST90013445.T1D)
PGP000517 |
Monti R et al. Am J Hum Genet (2024)
Type 1 diabetes (T1D) type 1 diabetes mellitus 63,182
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003993/ScoringFiles/PGS003993.txt.gz
PGS003998
(lassosum.auto.GCST004773.T2D)
PGP000517 |
Monti R et al. Am J Hum Genet (2024)
Type 2 diabetes (T2D) type 2 diabetes mellitus 5,548
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003998/ScoringFiles/PGS003998.txt.gz
PGS004009
(lassosum.auto.GCST90013445.T1D)
PGP000517 |
Monti R et al. Am J Hum Genet (2024)
Type 1 diabetes (T1D) type 1 diabetes mellitus 4,031
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004009/ScoringFiles/PGS004009.txt.gz
PGS004014
(lassosum.CV.GCST004773.T2D)
PGP000517 |
Monti R et al. Am J Hum Genet (2024)
Type 2 diabetes (T2D) type 2 diabetes mellitus 95,649
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004014/ScoringFiles/PGS004014.txt.gz
PGS004020
(lassosum.CV.GCST90013445.T1D)
PGP000517 |
Monti R et al. Am J Hum Genet (2024)
Type 1 diabetes (T1D) type 1 diabetes mellitus 6,682
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004020/ScoringFiles/PGS004020.txt.gz
PGS004024
(ldpred2.auto.GCST004773.T2D)
PGP000517 |
Monti R et al. Am J Hum Genet (2024)
Type 2 diabetes (T2D) type 2 diabetes mellitus 958,046
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004024/ScoringFiles/PGS004024.txt.gz
PGS004035
(ldpred2.auto.GCST90013445.T1D)
PGP000517 |
Monti R et al. Am J Hum Genet (2024)
Type 1 diabetes (T1D) type 1 diabetes mellitus 56,562
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004035/ScoringFiles/PGS004035.txt.gz
PGS004039
(ldpred2.CV.GCST004773.T2D)
PGP000517 |
Monti R et al. Am J Hum Genet (2024)
Type 2 diabetes (T2D) type 2 diabetes mellitus 958,046
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004039/ScoringFiles/PGS004039.txt.gz
PGS004052
(megaprs.auto.GCST004773.T2D)
PGP000517 |
Monti R et al. Am J Hum Genet (2024)
Type 2 diabetes (T2D) type 2 diabetes mellitus 800,598
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004052/ScoringFiles/PGS004052.txt.gz
PGS004063
(megaprs.auto.GCST90013445.T1D)
PGP000517 |
Monti R et al. Am J Hum Genet (2024)
Type 1 diabetes (T1D) type 1 diabetes mellitus 56,288
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004063/ScoringFiles/PGS004063.txt.gz
PGS004068
(megaprs.CV.GCST004773.T2D)
PGP000517 |
Monti R et al. Am J Hum Genet (2024)
Type 2 diabetes (T2D) type 2 diabetes mellitus 800,598
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004068/ScoringFiles/PGS004068.txt.gz
PGS004078
(megaprs.CV.GCST90013445.T1D)
PGP000517 |
Monti R et al. Am J Hum Genet (2024)
Type 1 diabetes (T1D) type 1 diabetes mellitus 56,288
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004078/ScoringFiles/PGS004078.txt.gz
PGS004082
(prscs.auto.GCST004773.T2D)
PGP000517 |
Monti R et al. Am J Hum Genet (2024)
Type 2 diabetes (T2D) type 2 diabetes mellitus 1,043,329
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004082/ScoringFiles/PGS004082.txt.gz
PGS004093
(prscs.auto.GCST90013445.T1D)
PGP000517 |
Monti R et al. Am J Hum Genet (2024)
Type 1 diabetes (T1D) type 1 diabetes mellitus 61,651
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004093/ScoringFiles/PGS004093.txt.gz
PGS004102
(prscs.CV.GCST90013445.T1D)
PGP000517 |
Monti R et al. Am J Hum Genet (2024)
Type 1 diabetes (T1D) type 1 diabetes mellitus 61,651
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004102/ScoringFiles/PGS004102.txt.gz
PGS004106
(pt_clump.auto.GCST004773.T2D)
PGP000517 |
Monti R et al. Am J Hum Genet (2024)
Type 2 diabetes (T2D) type 2 diabetes mellitus 35
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004106/ScoringFiles/PGS004106.txt.gz
PGS004117
(pt_clump.auto.GCST90013445.T1D)
PGP000517 |
Monti R et al. Am J Hum Genet (2024)
Type 1 diabetes (T1D) type 1 diabetes mellitus 131
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004117/ScoringFiles/PGS004117.txt.gz
PGS004122
(pt_clump_nested.CV.GCST004773.T2D)
PGP000517 |
Monti R et al. Am J Hum Genet (2024)
Type 2 diabetes (T2D) type 2 diabetes mellitus 297
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004122/ScoringFiles/PGS004122.txt.gz
PGS004132
(pt_clump_nested.CV.GCST90013445.T1D)
PGP000517 |
Monti R et al. Am J Hum Genet (2024)
Type 1 diabetes (T1D) type 1 diabetes mellitus 354
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004132/ScoringFiles/PGS004132.txt.gz
PGS004136
(sbayesr.auto.GCST004773.T2D)
PGP000517 |
Monti R et al. Am J Hum Genet (2024)
Type 2 diabetes (T2D) type 2 diabetes mellitus 930,497
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004136/ScoringFiles/PGS004136.txt.gz
PGS004147
(sbayesr.auto.GCST90013445.T1D)
PGP000517 |
Monti R et al. Am J Hum Genet (2024)
Type 1 diabetes (T1D) type 1 diabetes mellitus 45,996
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004147/ScoringFiles/PGS004147.txt.gz
PGS004152
(UKBB_EnsPGS.GCST004773.T2D)
PGP000517 |
Monti R et al. Am J Hum Genet (2024)
Type 2 diabetes (T2D) type 2 diabetes mellitus 1,071,786
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004152/ScoringFiles/PGS004152.txt.gz
PGS004162
(UKBB_EnsPGS.GCST90013445.T1D)
PGP000517 |
Monti R et al. Am J Hum Genet (2024)
Type 1 diabetes (T1D) type 1 diabetes mellitus 62,645
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004162/ScoringFiles/PGS004162.txt.gz
PGS004171
(t1d_1)
PGP000520 |
Raben TG et al. Sci Rep (2023)
Type 1 diabetes type 1 diabetes mellitus 520
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004171/ScoringFiles/PGS004171.txt.gz
PGS004172
(t1d_2)
PGP000520 |
Raben TG et al. Sci Rep (2023)
Type 1 diabetes type 1 diabetes mellitus 70
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004172/ScoringFiles/PGS004172.txt.gz
PGS004173
(t1d_3)
PGP000520 |
Raben TG et al. Sci Rep (2023)
Type 1 diabetes type 1 diabetes mellitus 295
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004173/ScoringFiles/PGS004173.txt.gz
PGS004174
(t1d_4)
PGP000520 |
Raben TG et al. Sci Rep (2023)
Type 1 diabetes type 1 diabetes mellitus 49
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004174/ScoringFiles/PGS004174.txt.gz
PGS004175
(t1d_5)
PGP000520 |
Raben TG et al. Sci Rep (2023)
Type 1 diabetes type 1 diabetes mellitus 315
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004175/ScoringFiles/PGS004175.txt.gz
PGS004181
(t2d_1)
PGP000520 |
Raben TG et al. Sci Rep (2023)
Type 2 diabetes type 2 diabetes mellitus 10,202
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004181/ScoringFiles/PGS004181.txt.gz
PGS004182
(t2d_2)
PGP000520 |
Raben TG et al. Sci Rep (2023)
Type 2 diabetes type 2 diabetes mellitus 10,778
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004182/ScoringFiles/PGS004182.txt.gz
PGS004183
(t2d_3)
PGP000520 |
Raben TG et al. Sci Rep (2023)
Type 2 diabetes type 2 diabetes mellitus 8,154
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004183/ScoringFiles/PGS004183.txt.gz
PGS004184
(t2d_4)
PGP000520 |
Raben TG et al. Sci Rep (2023)
Type 2 diabetes type 2 diabetes mellitus 9,645
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004184/ScoringFiles/PGS004184.txt.gz
PGS004185
(t2d_5)
PGP000520 |
Raben TG et al. Sci Rep (2023)
Type 2 diabetes type 2 diabetes mellitus 3,277
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004185/ScoringFiles/PGS004185.txt.gz
PGS004223
(PRS139_T2D)
PGP000523 |
Lin J et al. Sci Total Environ (2023)
Type 2 diabetes type 2 diabetes mellitus 139
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004223/ScoringFiles/PGS004223.txt.gz
PGS004225
(PRS46_T2DEastAsia)
PGP000526 |
Liu J et al. Nutrients (2023)
Type 2 diabetes type 2 diabetes mellitus 46
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004225/ScoringFiles/PGS004225.txt.gz
PGS004226
(PRS50_T2DEur)
PGP000526 |
Liu J et al. Nutrients (2023)
Type 2 diabetes type 2 diabetes mellitus 50
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004226/ScoringFiles/PGS004226.txt.gz
PGS004310
(GenoBoost_type_2_diabetes_0)
PGP000546 |
Ohta R et al. Nat Commun (2024)
Type 2 diabetes (T2D) type 2 diabetes mellitus 7,000
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004310/ScoringFiles/PGS004310.txt.gz
PGS004311
(GenoBoost_type_2_diabetes_1)
PGP000546 |
Ohta R et al. Nat Commun (2024)
Type 2 diabetes (T2D) type 2 diabetes mellitus 4,000
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004311/ScoringFiles/PGS004311.txt.gz
PGS004312
(GenoBoost_type_2_diabetes_2)
PGP000546 |
Ohta R et al. Nat Commun (2024)
Type 2 diabetes (T2D) type 2 diabetes mellitus 7,000
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004312/ScoringFiles/PGS004312.txt.gz
PGS004313
(GenoBoost_type_2_diabetes_3)
PGP000546 |
Ohta R et al. Nat Commun (2024)
Type 2 diabetes (T2D) type 2 diabetes mellitus 8,000
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004313/ScoringFiles/PGS004313.txt.gz
PGS004314
(GenoBoost_type_2_diabetes_4)
PGP000546 |
Ohta R et al. Nat Commun (2024)
Type 2 diabetes (T2D) type 2 diabetes mellitus 6,000
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004314/ScoringFiles/PGS004314.txt.gz
PGS004323
(PRS91_T2D)
PGP000557 |
Tan Q et al. J Hazard Mater (2023)
Type 2 diabetes type 2 diabetes mellitus 91
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004323/ScoringFiles/PGS004323.txt.gz
PGS004499
(disease.T2D.score)
PGP000561 |
Jung H et al. Commun Biol (2024)
Type 2 diabetes (T2D) type 2 diabetes mellitus 1,059,939
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004499/ScoringFiles/PGS004499.txt.gz
PGS004569
(meta.T2D.score)
PGP000561 |
Jung H et al. Commun Biol (2024)
Type 2 diabetes (T2D) type 2 diabetes mellitus 1,059,939
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004569/ScoringFiles/PGS004569.txt.gz
PGS004602
(PRS424_T2D)
PGP000580 |
Zhuang P et al. Diabetes Care (2021)
Type 2 diabetes (T2D) type 2 diabetes mellitus 424
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004602/ScoringFiles/PGS004602.txt.gz
PGS004615
(PGS_weights_TMM_All_of_1group)
PGP000593 |
Ojima T et al. Nat Genet (2024)
Type 2 diabetes (T2D) type 2 diabetes mellitus 855,161
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004615/ScoringFiles/PGS004615.txt.gz
PGS004616
(PGS_weights_TMM_HighBMI_of_2groups)
PGP000593 |
Ojima T et al. Nat Genet (2024)
Type 2 diabetes (T2D) type 2 diabetes mellitus 855,161
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004616/ScoringFiles/PGS004616.txt.gz
PGS004617
(PGS_weights_TMM_LowBMI_of_2groups)
PGP000593 |
Ojima T et al. Nat Genet (2024)
Type 2 diabetes (T2D) type 2 diabetes mellitus 855,161
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004617/ScoringFiles/PGS004617.txt.gz
PGS004618
(PGS_weights_BBJ2nd_All_of_1group)
PGP000593 |
Ojima T et al. Nat Genet (2024)
Type 2 diabetes (T2D) type 2 diabetes mellitus 728,824
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004618/ScoringFiles/PGS004618.txt.gz
PGS004619
(PGS_weights_BBJ2nd_HighBMI_of_2groups)
PGP000593 |
Ojima T et al. Nat Genet (2024)
Type 2 diabetes (T2D) type 2 diabetes mellitus 728,824
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004619/ScoringFiles/PGS004619.txt.gz
PGS004620
(PGS_weights_BBJ2nd_LowBMI_of_2groups)
PGP000593 |
Ojima T et al. Nat Genet (2024)
Type 2 diabetes (T2D) type 2 diabetes mellitus 728,824
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004620/ScoringFiles/PGS004620.txt.gz
PGS004837
(t2d_PRSmix_eur)
PGP000604 |
Truong B et al. Cell Genom (2024)
Type 2 diabetes (T2D) type 2 diabetes mellitus 3,306,136
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004837/ScoringFiles/PGS004837.txt.gz
PGS004838
(t2d_PRSmix_sas)
PGP000604 |
Truong B et al. Cell Genom (2024)
Type 2 diabetes (T2D) type 2 diabetes mellitus 6,586,458
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004838/ScoringFiles/PGS004838.txt.gz
PGS004839
(t2d_PRSmixPlus_eur)
PGP000604 |
Truong B et al. Cell Genom (2024)
Type 2 diabetes (T2D) type 2 diabetes mellitus 4,594,694
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004839/ScoringFiles/PGS004839.txt.gz
PGS004840
(t2d_PRSmixPlus_sas)
PGP000604 |
Truong B et al. Cell Genom (2024)
Type 2 diabetes (T2D) type 2 diabetes mellitus 6,586,458
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004840/ScoringFiles/PGS004840.txt.gz
PGS004859
(T2D_PRS_CS)
PGP000605 |
Deutsch AJ et al. Diabetes Care (2023)
Type 2 diabetes (T2D) type 2 diabetes mellitus 1,108,235
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004859/ScoringFiles/PGS004859.txt.gz
PGS004868
(T2DPGS)
PGP000617 |
Yun JS et al. Cardiovasc Diabetol (2022)
Type 2 diabetes (T2D) type 2 diabetes mellitus 6,580,804
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004868/ScoringFiles/PGS004868.txt.gz
PGS004870
(INTERVENE_MegaPRS_T2D)
PGP000618 |
Jermy B et al. Nat Commun (2024)
Type 2 diabetes (T2D) type 2 diabetes mellitus 930,506
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004870/ScoringFiles/PGS004870.txt.gz
PGS004874
(INTERVENE_MegaPRS_T1D)
PGP000618 |
Jermy B et al. Nat Commun (2024)
Type 1 diabetes (T1D) type 1 diabetes mellitus 56,916
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004874/ScoringFiles/PGS004874.txt.gz
PGS004887
(T2D_gePGS)
PGP000619 |
Mandla R et al. Genome Med (2024)
Type 2 diabetes (T2D) type 2 diabetes mellitus 1,117,628
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004887/ScoringFiles/PGS004887.txt.gz
PGS004923
(T2D_metaGRS)
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Pre
Type 2 diabetes (T2D) type 2 diabetes mellitus 1,349,896
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004923/ScoringFiles/PGS004923.txt.gz
PGS005021
(Phe_250_2_ldpred_AFRss_afrld)
PGP000679 |
Gunn S et al. HGG Adv (2024)
Type 2 diabetes (T2D) (PheCode 250.2) type 2 diabetes mellitus 1,286,612
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005021/ScoringFiles/PGS005021.txt.gz
PGS005022
(Phe_250_2_ldpred_EURss_eurld)
PGP000679 |
Gunn S et al. HGG Adv (2024)
Type 2 diabetes (T2D) (PheCode 250.2) type 2 diabetes mellitus 1,286,612
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005022/ScoringFiles/PGS005022.txt.gz
PGS005023
(Phe_250_2_ldpred_HISss_amrld)
PGP000679 |
Gunn S et al. HGG Adv (2024)
Type 2 diabetes (T2D) (PheCode 250.2) type 2 diabetes mellitus 1,286,612
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005023/ScoringFiles/PGS005023.txt.gz
PGS005024
(Phe_250_2_ldpred_METAss_afrld)
PGP000679 |
Gunn S et al. HGG Adv (2024)
Type 2 diabetes (T2D) (PheCode 250.2) type 2 diabetes mellitus 1,286,612
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005024/ScoringFiles/PGS005024.txt.gz
PGS005025
(Phe_250_2_ldpred_METAss_amrld)
PGP000679 |
Gunn S et al. HGG Adv (2024)
Type 2 diabetes (T2D) (PheCode 250.2) type 2 diabetes mellitus 1,286,612
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005025/ScoringFiles/PGS005025.txt.gz
PGS005026
(Phe_250_2_ldpred_METAss_eurld)
PGP000679 |
Gunn S et al. HGG Adv (2024)
Type 2 diabetes (T2D) (PheCode 250.2) type 2 diabetes mellitus 1,286,612
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005026/ScoringFiles/PGS005026.txt.gz
PGS005027
(Phe_250_2_prscs_AFRss_afrld)
PGP000679 |
Gunn S et al. HGG Adv (2024)
Type 2 diabetes (T2D) (PheCode 250.2) type 2 diabetes mellitus 1,273,897
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005027/ScoringFiles/PGS005027.txt.gz
PGS005028
(Phe_250_2_prscs_EURss_eurld)
PGP000679 |
Gunn S et al. HGG Adv (2024)
Type 2 diabetes (T2D) (PheCode 250.2) type 2 diabetes mellitus 1,273,897
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005028/ScoringFiles/PGS005028.txt.gz
PGS005029
(Phe_250_2_prscs_HISss_amrld)
PGP000679 |
Gunn S et al. HGG Adv (2024)
Type 2 diabetes (T2D) (PheCode 250.2) type 2 diabetes mellitus 1,273,897
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005029/ScoringFiles/PGS005029.txt.gz
PGS005030
(Phe_250_2_prscs_METAss_afrld)
PGP000679 |
Gunn S et al. HGG Adv (2024)
Type 2 diabetes (T2D) (PheCode 250.2) type 2 diabetes mellitus 1,273,897
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005030/ScoringFiles/PGS005030.txt.gz
PGS005031
(Phe_250_2_prscs_METAss_amrld)
PGP000679 |
Gunn S et al. HGG Adv (2024)
Type 2 diabetes (T2D) (PheCode 250.2) type 2 diabetes mellitus 1,273,897
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005031/ScoringFiles/PGS005031.txt.gz
PGS005032
(Phe_250_2_prscs_METAss_eurld)
PGP000679 |
Gunn S et al. HGG Adv (2024)
Type 2 diabetes (T2D) (PheCode 250.2) type 2 diabetes mellitus 1,273,897
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005032/ScoringFiles/PGS005032.txt.gz
PGS005033
(Phe_250_2_prscsx_METAweight)
PGP000679 |
Gunn S et al. HGG Adv (2024)
Type 2 diabetes (T2D) (PheCode 250.2) type 2 diabetes mellitus 1,277,826
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005033/ScoringFiles/PGS005033.txt.gz

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM)
Evaluated Score PGS Sample Set ID
(PSS)
Performance Source Trait PGS Effect Sizes
(per SD change)
Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM000023 PGS000014
(GPS_T2D)
PSS000017|
European Ancestry|
288,978 individuals
PGP000006 |
Khera AV et al. Nat Genet (2018)
Reported Trait: Type 2 diabetes AUROC: 0.73 [0.72, 0.73] Nagelkerke’s R2 (estimate of variance explained by the PGS after covariate adjustment): 0.029 age; sex; Ancestry PC 1-4; genotyping chip
PPM002477 PGS000014
(GPS_T2D)
PSS001117|
European Ancestry|
68,229 individuals
PGP000218 |
He Y et al. Diabetes Care (2021)
|Ext.
Reported Trait: Incident type II diabetes C-index: 0.709 [0.696, 0.722] Hazard ratio (HR, top 10% vs. remaining 90%): 2.0 [1.73, 2.31] Sex, age, principal components, assessment center
PPM002478 PGS000014
(GPS_T2D)
PSS001117|
European Ancestry|
68,229 individuals
PGP000218 |
He Y et al. Diabetes Care (2021)
|Ext.
Reported Trait: Incident type II diabetes in males C-index: 0.68 [0.663, 0.697] Age, principal components and assessment center
PPM002479 PGS000014
(GPS_T2D)
PSS001117|
European Ancestry|
68,229 individuals
PGP000218 |
He Y et al. Diabetes Care (2021)
|Ext.
Reported Trait: Incident type II diabetes in females C-index: 0.705 [0.682, 0.728] Age, principal components and assessment center
PPM002480 PGS000014
(GPS_T2D)
PSS001117|
European Ancestry|
68,229 individuals
PGP000218 |
He Y et al. Diabetes Care (2021)
|Ext.
Reported Trait: Incident type II diabetes C-index: 0.776 [0.764, 0.788] Sex, age, principal components, assessment center, polyexposure score
PPM002481 PGS000014
(GPS_T2D)
PSS001117|
European Ancestry|
68,229 individuals
PGP000218 |
He Y et al. Diabetes Care (2021)
|Ext.
Reported Trait: Incident type II diabetes C-index: 0.844 [0.834, 0.854] Sex, age, principal components, assessment center, clinical risk score
PPM002482 PGS000014
(GPS_T2D)
PSS001117|
European Ancestry|
68,229 individuals
PGP000218 |
He Y et al. Diabetes Care (2021)
|Ext.
Reported Trait: Incident type II diabetes C-index: 0.855 [0.845, 0.865] Sex, age, principal components, assessment center, polyexposure socre, clinical risk score
PPM002483 PGS000014
(GPS_T2D)
PSS001117|
European Ancestry|
68,229 individuals
PGP000218 |
He Y et al. Diabetes Care (2021)
|Ext.
Reported Trait: Incident type II diabetes in females C-index: 0.786 [0.765, 0.807] Age, principal components, assessment center, polyexposure score
PPM002485 PGS000014
(GPS_T2D)
PSS001117|
European Ancestry|
68,229 individuals
PGP000218 |
He Y et al. Diabetes Care (2021)
|Ext.
Reported Trait: Incident type II diabetes in females C-index: 0.859 [0.842, 0.876] Sex, age, principal components, assessment center, clinical risk score
PPM002486 PGS000014
(GPS_T2D)
PSS001117|
European Ancestry|
68,229 individuals
PGP000218 |
He Y et al. Diabetes Care (2021)
|Ext.
Reported Trait: Incident type II diabetes in males C-index: 0.749 [0.734, 0.764] Age, principal components, assessment center, polyexposure score
PPM002487 PGS000014
(GPS_T2D)
PSS001117|
European Ancestry|
68,229 individuals
PGP000218 |
He Y et al. Diabetes Care (2021)
|Ext.
Reported Trait: Incident type II diabetes in males C-index: 0.821 [0.808, 0.834] Age, principal components, assessment center, polyexposure socre, clinical risk score
PPM002488 PGS000014
(GPS_T2D)
PSS001117|
European Ancestry|
68,229 individuals
PGP000218 |
He Y et al. Diabetes Care (2021)
|Ext.
Reported Trait: Incident type II diabetes in males C-index: 0.834 [0.821, 0.847] Sex, age, principal components, assessment center, clinical risk score
PPM002484 PGS000014
(GPS_T2D)
PSS001117|
European Ancestry|
68,229 individuals
PGP000218 |
He Y et al. Diabetes Care (2021)
|Ext.
Reported Trait: Incident type II diabetes in females C-index: 0.869 [0.853, 0.885] Age, principal components, assessment center, polyexposure socre, clinical risk score
PPM015522 PGS000014
(GPS_T2D)
PSS009971|
Multi-ancestry (including European)|
36,422 individuals
PGP000381 |
Hao L et al. Nat Med (2022)
|Ext.
Reported Trait: Type 2 diabetes mellitus OR: 1.75 [1.57, 1.95] 4 genetic PCs
PPM019100 PGS000014
(GPS_T2D)
PSS011181|
Ancestry Not Reported|
3,071 individuals
PGP000504 |
Duschek E et al. Sci Rep (2023)
|Ext.
Reported Trait: Incident type 2 diabetes AUROC: 0.613 [0.565, 0.657]
PPM019098 PGS000014
(GPS_T2D)
PSS011181|
Ancestry Not Reported|
3,071 individuals
PGP000504 |
Duschek E et al. Sci Rep (2023)
|Ext.
Reported Trait: Incident type 2 diabetes OR: 1.67 [1.37, 2.03] Age, Sex, BMI, Physical activity, FamRS
PPM019099 PGS000014
(GPS_T2D)
PSS011181|
Ancestry Not Reported|
3,071 individuals
PGP000504 |
Duschek E et al. Sci Rep (2023)
|Ext.
Reported Trait: Prevelant type 2 diabetes AUROC: 0.869 [0.842, 0.896]
PPM019097 PGS000014
(GPS_T2D)
PSS011181|
Ancestry Not Reported|
3,071 individuals
PGP000504 |
Duschek E et al. Sci Rep (2023)
|Ext.
Reported Trait: Prevelant type 2 diabetes OR: 6.21 [5.06, 7.74] Age, Sex, BMI, Physical activity, FamRS
PPM021428 PGS000014
(GPS_T2D)
PSS011737|
European Ancestry|
109,021 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Type 2 diabetes OR: 1.51 [1.48, 1.55] AUROC: 0.7 [0.695, 0.705] Age at baseline, sex (PGS adjusted for 20 PCs prior to model fitting)
PPM021437 PGS000014
(GPS_T2D)
PSS011747|
European Ancestry|
245,177 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Type 2 diabetes OR: 1.71 [1.67, 1.74] AUROC: 0.731 [0.726, 0.736] Age at baseline, sex assessment centre (PGS adjusted for 20 PCs prior to model fitting)
PPM021458 PGS000014
(GPS_T2D)
PSS011738|
European Ancestry|
38,941 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Incident type 2 diabetes HR: 1.58 [1.47, 1.7] C-index: 0.737 [0.719, 0.754] Age at baseline, sex (PGS adjusted for 20 PCs prior to model fitting)
PPM021465 PGS000014
(GPS_T2D)
PSS011746|
European Ancestry|
232,808 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Incident type 2 diabetes HR: 1.45 [1.42, 1.49] C-index: 0.686 [0.679, 0.692] Age at baseline, sex assessment centre (PGS adjusted for 20 PCs prior to model fitting)
PPM021484 PGS000014
(GPS_T2D)
PSS011735|
African Ancestry|
44,346 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Type 2 diabetes OR: 1.21 [1.17, 1.24] AUROC: 0.717 [0.71, 0.723] Age at baseline, sex (PGS adjusted for 20 PCs prior to model fitting)
PPM021506 PGS000014
(GPS_T2D)
PSS011736|
Hispanic or Latin American Ancestry|
33,652 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Type 2 diabetes OR: 1.39 [1.34, 1.44] AUROC: 0.757 [0.75, 0.764] Age at baseline, sex (PGS adjusted for 20 PCs prior to model fitting)
PPM021531 PGS000014
(GPS_T2D)
PSS011740|
East Asian Ancestry|
1,149 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Incident type 2 diabetes OR: 0.99 [0.85, 1.16] AUROC: 0.585 [0.541, 0.629] Age at baseline, sex (PGS adjusted for 20 PCs prior to model fitting)
PPM021553 PGS000014
(GPS_T2D)
PSS011741|
South Asian Ancestry|
852 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Incident type 2 diabetes OR: 1.03 [0.87, 1.21] AUROC: 0.639 [0.596, 0.683] Age at baseline, sex (PGS adjusted for 20 PCs prior to model fitting)
PPM021571 PGS000014
(GPS_T2D)
PSS011739|
Additional Asian Ancestries|
870 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Incident type 2 diabetes OR: 0.82 [0.69, 0.97] AUROC: 0.662 [0.618, 0.706] Age at baseline, sex (PGS adjusted for 20 PCs prior to model fitting)
PPM021589 PGS000014
(GPS_T2D)
PSS011743|
African Ancestry|
6,871 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Type 2 diabetes OR: 1.27 [1.18, 1.38] AUROC: 0.714 [0.695, 0.733] Age at baseline, sex assessment centre (PGS adjusted for 20 PCs prior to model fitting)
PPM021615 PGS000014
(GPS_T2D)
PSS011745|
East Asian Ancestry|
1,432 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Type 2 diabetes OR: 1.28 [1.01, 1.61] AUROC: 0.705 [0.648, 0.763] Age at baseline, sex assessment centre (PGS adjusted for 20 PCs prior to model fitting)
PPM021635 PGS000014
(GPS_T2D)
PSS011749|
South Asian Ancestry|
6,992 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Type 2 diabetes OR: 1.48 [1.39, 1.58] AUROC: 0.711 [0.696, 0.726] Age at baseline, sex assessment centre (PGS adjusted for 20 PCs prior to model fitting)
PPM021653 PGS000014
(GPS_T2D)
PSS011742|
African Ancestry|
6,019 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Incident type 2 diabetes HR: 1.12 [1.01, 1.23] C-index: 0.641 [0.614, 0.669] Age at baseline, sex assessment centre (PGS adjusted for 20 PCs prior to model fitting)
PPM021677 PGS000014
(GPS_T2D)
PSS011744|
East Asian Ancestry|
1,350 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Incident type 2 diabetes HR: 1.24 [0.9, 1.7] C-index: 0.684 [0.609, 0.758] Age at baseline, sex assessment centre (PGS adjusted for 20 PCs prior to model fitting)
PPM021699 PGS000014
(GPS_T2D)
PSS011748|
South Asian Ancestry|
5,685 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Incident type 2 diabetes HR: 1.14 [1.05, 1.24] C-index: 0.605 [0.582, 0.628] Age at baseline, sex assessment centre (PGS adjusted for 20 PCs prior to model fitting)
PPM000040 PGS000020
(dGRS1000)
PSS000025|
European Ancestry|
6,280 individuals
PGP000010 |
Läll K et al. Genet Med (2016)
Reported Trait: Incident type 2 diabetes HR: 1.48 [1.32, 1.66] C-index: 0.79 [0.771, 0.812] BMI category, smoking level, waist-to-hip ratio, waist circumference, physical activity level, history of high blood glucose, fruit and vegetable consumption, and sex. Cox age-as-time-scale
PPM000132 PGS000021
(GRS1)
PSS000083|
European Ancestry|
2,768 individuals
PGP000038 |
Patel KA et al. Diabetes (2016)
|Ext.
Reported Trait: Type 1 diabetes aetiology (non-monogenic) AUROC: 0.87 [0.86, 0.89] Testing the ability of the GRS to discriminate between two sets of cases: - Positive: individuals with type 1 diabetes - Negative: individuals with diabetes and a maturity-onset diabetes of young (MODY) mutation
PPM000041 PGS000021
(GRS1)
PSS000026|
European Ancestry|
223 individuals
PGP000011 |
Oram RA et al. Diabetes Care (2015)
Reported Trait: Severe insulin deficiency AUROC: 0.96 [0.94, 0.99] AUROC (without covariates): 0.87 islet auto-antibody status, body mass index (BMI), age at diagnosis
PPM000046 PGS000021
(GRS1)
PSS000030|
African Ancestry|
3,949 individuals
PGP000013 |
Onengut-Gumuscu S et al. Diabetes Care (2019)
|Ext.
Reported Trait: Type 1 diabetes AUROC: 0.798
PPM000049 PGS000021
(GRS1)
PSS000032|
European Ancestry|
374,000 individuals
PGP000014 |
Sharp SA et al. Diabetes Care (2019)
|Ext.
Reported Trait: Type 1 diabetes AUROC: 0.893
PPM000042 PGS000022
(T1D_GRS)
PSS000029|
European Ancestry|
1,447 individuals
PGP000012 |
Perry DJ et al. Sci Rep (2018)
Reported Trait: Type 1 diabetes AUROC: 0.8508 AUROCs are reported with respect to unrelated-control samples
PPM000043 PGS000022
(T1D_GRS)
PSS000028|
Hispanic or Latin American Ancestry|
252 individuals
PGP000012 |
Perry DJ et al. Sci Rep (2018)
Reported Trait: Type 1 diabetes AUROC: 0.9003 AUROCs are reported with respect to unrelated-control samples
PPM000044 PGS000022
(T1D_GRS)
PSS000027|
African Ancestry|
299 individuals
PGP000012 |
Perry DJ et al. Sci Rep (2018)
Reported Trait: Type 1 diabetes AUROC: 0.7522 AUROCs are reported with respect to unrelated-control samples
PPM000045 PGS000023
(AA_GRS)
PSS000030|
African Ancestry|
3,949 individuals
PGP000013 |
Onengut-Gumuscu S et al. Diabetes Care (2019)
Reported Trait: Type 1 diabetes AUROC: 0.87 NOTE: Evaluated using cross-validation on training samples (20% heldout, 1000 iterations)
PPM000047 PGS000023
(AA_GRS)
PSS000031|
African Ancestry|
145 individuals
PGP000013 |
Onengut-Gumuscu S et al. Diabetes Care (2019)
Reported Trait: Type 1 diabetes AUROC: 0.779
PPM018536 PGS000023
(AA_GRS)
PSS011012|
Multi-ancestry (including European)|
39,820 individuals
PGP000477 |
Deutsch AJ et al. Diabetes Care (2023)
|Ext.
Reported Trait: Type 1 diabetes AUROC: 0.781
PPM018537 PGS000023
(AA_GRS)
PSS011009|
Multi-ancestry (including European)|
57,643 individuals
PGP000477 |
Deutsch AJ et al. Diabetes Care (2023)
|Ext.
Reported Trait: Type 1 diabetes AUROC: 0.817
PPM018539 PGS000023
(AA_GRS)
PSS011011|
European Ancestry|
16,663 individuals
PGP000477 |
Deutsch AJ et al. Diabetes Care (2023)
|Ext.
Reported Trait: Type 1 diabetes PPV (+PRS): 97.0 %
PPV (reference): 86.0 %
eMERGE type 1 diabetes algorithm
PPM018541 PGS000023
(AA_GRS)
PSS011010|
Multi-ancestry (excluding European)|
40,980 individuals
PGP000477 |
Deutsch AJ et al. Diabetes Care (2023)
|Ext.
Reported Trait: Type 1 diabetes PPV (+PRS): 86.0 %
PPV (reference): 71.0 %
eMERGE type 1 diabetes algorithm
PPM018543 PGS000023
(AA_GRS)
PSS011013|
Multi-ancestry (excluding European)|
4,881 individuals
PGP000477 |
Deutsch AJ et al. Diabetes Care (2023)
|Ext.
Reported Trait: Type 1 diabetes PPV (+PRS): 83.0 %
PPV (reference): 53.0 %
eMERGE type 1 diabetes algorithm
PPM021725 PGS000023
(AA_GRS)
PSS011762|
European Ancestry|
8,417 individuals
PGP000665 |
Moreno-Grau S et al. Human Genomics (2024)
|Ext.
Reported Trait: Type 1 diabetes mellitus OR: 2.31 [2.0, 2.68] AUROC: 0.77
PPM000048 PGS000024
(GRS2)
PSS000032|
European Ancestry|
374,000 individuals
PGP000014 |
Sharp SA et al. Diabetes Care (2019)
Reported Trait: Type 1 diabetes AUROC: 0.921 Youden index: 0.698
PPM000753 PGS000024
(GRS2)
PSS000368|
Ancestry Not Reported|
7,798 individuals
PGP000091 |
Ferrat LA et al. Nat Med (2020)
|Ext.
Reported Trait: Type 1 diabetes (5 years horizon time; landmark age 2 years) AUROC: 0.93 autoantibodies, family history
PPM000754 PGS000024
(GRS2)
PSS000368|
Ancestry Not Reported|
7,798 individuals
PGP000091 |
Ferrat LA et al. Nat Med (2020)
|Ext.
Reported Trait: Type 1 diabetes (8 years horizon time; landmark age 2 years) AUROC: 0.87 autoantibodies, family history
PPM000755 PGS000024
(GRS2)
PSS000368|
Ancestry Not Reported|
7,798 individuals
PGP000091 |
Ferrat LA et al. Nat Med (2020)
|Ext.
Reported Trait: Type 1 diabetes (5 years horizon time; landmark age 4 years) AUROC: 0.96 autoantibodies, family history
PPM000751 PGS000024
(GRS2)
PSS000368|
Ancestry Not Reported|
7,798 individuals
PGP000091 |
Ferrat LA et al. Nat Med (2020)
|Ext.
Reported Trait: Type 1 diabetes (1 year horizon time; landmark age 2 years) AUROC: 0.96 autoantibodies, family history
PPM000752 PGS000024
(GRS2)
PSS000368|
Ancestry Not Reported|
7,798 individuals
PGP000091 |
Ferrat LA et al. Nat Med (2020)
|Ext.
Reported Trait: Type 1 diabetes (3 years horizon time; landmark age 2 years) AUROC: 0.94 autoantibodies, family history
PPM000750 PGS000024
(GRS2)
PSS000368|
Ancestry Not Reported|
7,798 individuals
PGP000091 |
Ferrat LA et al. Nat Med (2020)
|Ext.
Reported Trait: Type 1 diabetes (by age 8; landmark age 2 years) AUROC: 0.73 [0.7, 0.77]
PPM002249 PGS000024
(GRS2)
PSS001087|
European Ancestry|
3,930 individuals
PGP000211 |
Aly DM et al. Nat Genet (2021)
|Ext.
Reported Trait: Severe Insulin-Deficient Diabetes OR: 1.0 [0.93, 1.07] PC1-10 8 proxy variants were used to evaluate this score
PPM002250 PGS000024
(GRS2)
PSS001088|
European Ancestry|
3,869 individuals
PGP000211 |
Aly DM et al. Nat Genet (2021)
|Ext.
Reported Trait: Severe Insulin-Resistant Diabetes OR: 1.0 [0.93, 1.07] PC1-10 8 proxy variants were used to evaluate this score
PPM002251 PGS000024
(GRS2)
PSS001085|
European Ancestry|
4,116 individuals
PGP000211 |
Aly DM et al. Nat Genet (2021)
|Ext.
Reported Trait: Moderate Obesity-related Diabetes OR: 1.01 [0.95, 1.08] PC1-10 8 proxy variants were used to evaluate this score
PPM002252 PGS000024
(GRS2)
PSS001084|
European Ancestry|
5,597 individuals
PGP000211 |
Aly DM et al. Nat Genet (2021)
|Ext.
Reported Trait: Moderate Age-Related Diabetes OR: 0.99 [0.94, 1.04] PC1-10 8 proxy variants were used to evaluate this score
PPM002248 PGS000024
(GRS2)
PSS001086|
European Ancestry|
3,194 individuals
PGP000211 |
Aly DM et al. Nat Genet (2021)
|Ext.
Reported Trait: Severe Autoimmune Diabetes OR: 2.55 [2.28, 2.86] PC1-10 8 proxy variants were used to evaluate this score
PPM014801 PGS000024
(GRS2)
PSS009895|
European Ancestry|
1,168 individuals
PGP000338 |
Oram RA et al. Diabetes Care (2022)
|Ext.
Reported Trait: Diabetes autoantibody positive insulin sensitive AUROC: 0.864 [0.823, 0.905]
PPM014803 PGS000024
(GRS2)
PSS009893|
African Ancestry|
366 individuals
PGP000338 |
Oram RA et al. Diabetes Care (2022)
|Ext.
Reported Trait: Diabetes autoantibody positive insulin sensitive AUROC: 0.851 [0.805, 0.897]
PPM014805 PGS000024
(GRS2)
PSS009894|
Hispanic or Latin American Ancestry|
412 individuals
PGP000338 |
Oram RA et al. Diabetes Care (2022)
|Ext.
Reported Trait: Diabetes autoantibody positive insulin sensitive AUROC: 0.935 [0.906, 0.964]
PPM014807 PGS000024
(GRS2)
PSS009896|
Ancestry Not Reported|
99 individuals
PGP000338 |
Oram RA et al. Diabetes Care (2022)
|Ext.
Reported Trait: Diabetes autoantibody positive insulin sensitive AUROC: 0.79 [0.679, 0.902]
PPM018532 PGS000024
(GRS2)
PSS011012|
Multi-ancestry (including European)|
39,820 individuals
PGP000477 |
Deutsch AJ et al. Diabetes Care (2023)
|Ext.
Reported Trait: Type 1 diabetes AUROC: 0.875
PPM018533 PGS000024
(GRS2)
PSS011009|
Multi-ancestry (including European)|
57,643 individuals
PGP000477 |
Deutsch AJ et al. Diabetes Care (2023)
|Ext.
Reported Trait: Type 1 diabetes AUROC: 0.822
PPM018534 PGS000024
(GRS2)
PSS011014|
European Ancestry|
34,939 individuals
PGP000477 |
Deutsch AJ et al. Diabetes Care (2023)
|Ext.
Reported Trait: Type 1 diabetes AUROC: 0.888
PPM018535 PGS000024
(GRS2)
PSS011014|
European Ancestry|
34,939 individuals
PGP000477 |
Deutsch AJ et al. Diabetes Care (2023)
|Ext.
Reported Trait: Type 1 diabetes AUROC: 0.858
PPM018538 PGS000024
(GRS2)
PSS011011|
European Ancestry|
16,663 individuals
PGP000477 |
Deutsch AJ et al. Diabetes Care (2023)
|Ext.
Reported Trait: Type 1 diabetes PPV (+PRS): 100.0 %
PPV (reference): 86.0 %
eMERGE type 1 diabetes algorithm
PPM018540 PGS000024
(GRS2)
PSS011010|
Multi-ancestry (excluding European)|
40,980 individuals
PGP000477 |
Deutsch AJ et al. Diabetes Care (2023)
|Ext.
Reported Trait: Type 1 diabetes PPV (+PRS): 93.0 %
PPV (reference): 71.0 %
eMERGE type 1 diabetes algorithm
PPM018542 PGS000024
(GRS2)
PSS011014|
European Ancestry|
34,939 individuals
PGP000477 |
Deutsch AJ et al. Diabetes Care (2023)
|Ext.
Reported Trait: Type 1 diabetes PPV (+PRS): 97.0 %
PPV (reference): 71.0 %
eMERGE type 1 diabetes algorithm
PPM020098 PGS000024
(GRS2)
PSS011295|
Ancestry Not Reported|
1,798 individuals
PGP000519 |
Thomas NJ et al. Diabetes Care (2023)
|Ext.
Reported Trait: Type 1 diabetes vs autoantibody negative T2D p-value (inferior to): 0.0001
PPM021124 PGS000024
(GRS2)
PSS011531|
European Ancestry|
9,465 individuals
PGP000614 |
Qu HQ et al. Diabetes Obes Metab (2021)
|Ext.
Reported Trait: Type 1 diabetes β: -0.22 AUROC: 0.87
PPM021125 PGS000024
(GRS2)
PSS011532|
European Ancestry|
9,450 individuals
PGP000614 |
Qu HQ et al. Diabetes Obes Metab (2021)
|Ext.
Reported Trait: Type 1 diabetes β: -0.234 AUROC: 0.862
PPM000062 PGS000031
(GRSt)
PSS000044|
European Ancestry|
3,471 individuals
PGP000020 |
Vassy JL et al. Diabetes (2014)
Reported Trait: Incident type 2 diabetes cases HR: 1.06 [1.04, 1.08] C-index: 0.906 [0.892, 0.92] age, sex, family history (parents), body mass index, systolic blood pressure, fasting glucose, log-HDL cholesterol, log-triglyceride levels Results from the "Clinical model"
PPM000063 PGS000031
(GRSt)
PSS000043|
European Ancestry|
1,650 individuals
PGP000020 |
Vassy JL et al. Diabetes (2014)
Reported Trait: Incident type 2 diabetes cases HR: 1.06 [1.02, 1.1] C-index: 0.853 [0.81, 0.896] age, sex, family history (parents), body mass index, systolic blood pressure, fasting glucose, log-HDL cholesterol, log-triglyceride levels Results from the "Clinical model"
PPM000064 PGS000031
(GRSt)
PSS000042|
African Ancestry|
820 individuals
PGP000020 |
Vassy JL et al. Diabetes (2014)
Reported Trait: Incident type 2 diabetes cases HR: 1.05 [1.0, 1.09] C-index: 0.771 [0.727, 0.814] age, sex, family history (parents), body mass index, systolic blood pressure, fasting glucose, log-HDL cholesterol, log-triglyceride levels Results from the "Clinical model", SNPs were not weighted by their effect size as the betas were measure in Europeans
PPM000065 PGS000032
(GRSB)
PSS000044|
European Ancestry|
3,471 individuals
PGP000020 |
Vassy JL et al. Diabetes (2014)
Reported Trait: Incident type 2 diabetes cases HR: 1.1 [1.06, 1.14] age, sex, family history (parents), body mass index, systolic blood pressure, fasting glucose, log-HDL cholesterol, log-triglyceride levels Results from the "Clinical model"
PPM000066 PGS000032
(GRSB)
PSS000043|
European Ancestry|
1,650 individuals
PGP000020 |
Vassy JL et al. Diabetes (2014)
Reported Trait: Incident type 2 diabetes cases HR: 1.09 [1.02, 1.17] age, sex, family history (parents), body mass index, systolic blood pressure, fasting glucose, log-HDL cholesterol, log-triglyceride levels Results from the "Clinical model"
PPM000067 PGS000032
(GRSB)
PSS000042|
African Ancestry|
820 individuals
PGP000020 |
Vassy JL et al. Diabetes (2014)
Reported Trait: Incident type 2 diabetes cases HR: 1.06 [0.99, 1.15] age, sex, family history (parents), body mass index, systolic blood pressure, fasting glucose, log-HDL cholesterol, log-triglyceride levels Results from the "Clinical model", SNPs were not weighted by their effect size as the betas were measure in Europeans
PPM002415 PGS000032
(GRSB)
PSS001092|
Ancestry Not Reported|
5,740 individuals
PGP000214 |
Aksit MA et al. J Clin Endocrinol Metab (2020)
|Ext.
Reported Trait: Cystic-fibrosis related diabetes onset HR: 1.192 PCs(1-4), site of recruitment
PPM000068 PGS000033
(GRSIR)
PSS000044|
European Ancestry|
3,471 individuals
PGP000020 |
Vassy JL et al. Diabetes (2014)
Reported Trait: Incident type 2 diabetes cases HR: 0.98 [0.93, 1.04] age, sex, family history (parents), body mass index, systolic blood pressure, fasting glucose, log-HDL cholesterol, log-triglyceride levels Results from the "Clinical model"
PPM000069 PGS000033
(GRSIR)
PSS000043|
European Ancestry|
1,650 individuals
PGP000020 |
Vassy JL et al. Diabetes (2014)
Reported Trait: Incident type 2 diabetes cases HR: 1.01 [0.91, 1.12] age, sex, family history (parents), body mass index, systolic blood pressure, fasting glucose, log-HDL cholesterol, log-triglyceride levels Results from the "Clinical model"
PPM000070 PGS000033
(GRSIR)
PSS000042|
African Ancestry|
820 individuals
PGP000020 |
Vassy JL et al. Diabetes (2014)
Reported Trait: Incident type 2 diabetes cases HR: 1.06 [0.99, 1.15] age, sex, family history (parents), body mass index, systolic blood pressure, fasting glucose, log-HDL cholesterol, log-triglyceride levels Results from the "Clinical model", SNPs were not weighted by their effect size as the betas were measure in Europeans
PPM000080 PGS000036
(gePS_T2D)
PSS000054|
European Ancestry|
324,870 individuals
PGP000024 |
Udler MS et al. Endocr Rev (2019)
|Ext.
Reported Trait: Type 2 diabetes AUROC: 0.66 genotyping array, first 6 PCs of ancestry
PPM000081 PGS000036
(gePS_T2D)
PSS000054|
European Ancestry|
324,870 individuals
PGP000024 |
Udler MS et al. Endocr Rev (2019)
|Ext.
Reported Trait: Type 2 diabetes AUROC: 0.73 age, sex, genotyping array, first 6 PCs of ancestry
PPM014802 PGS000036
(gePS_T2D)
PSS009895|
European Ancestry|
1,168 individuals
PGP000338 |
Oram RA et al. Diabetes Care (2022)
|Ext.
Reported Trait: Diabetes autoantibody positive insulin sensitive AUROC: 0.661 [0.606, 0.716]
PPM014804 PGS000036
(gePS_T2D)
PSS009893|
African Ancestry|
366 individuals
PGP000338 |
Oram RA et al. Diabetes Care (2022)
|Ext.
Reported Trait: Diabetes autoantibody positive insulin sensitive AUROC: 0.574 [0.506, 0.643]
PPM014806 PGS000036
(gePS_T2D)
PSS009894|
Hispanic or Latin American Ancestry|
412 individuals
PGP000338 |
Oram RA et al. Diabetes Care (2022)
|Ext.
Reported Trait: Diabetes autoantibody positive insulin sensitive AUROC: 0.722 [0.667, 0.778]
PPM014808 PGS000036
(gePS_T2D)
PSS009896|
Ancestry Not Reported|
99 individuals
PGP000338 |
Oram RA et al. Diabetes Care (2022)
|Ext.
Reported Trait: Diabetes autoantibody positive insulin sensitive AUROC: 0.677 [0.532, 0.822]
PPM021427 PGS000036
(gePS_T2D)
PSS011737|
European Ancestry|
109,021 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Type 2 diabetes OR: 1.53 [1.5, 1.56] AUROC: 0.701 [0.696, 0.706] Age at baseline, sex (PGS adjusted for 20 PCs prior to model fitting)
PPM021436 PGS000036
(gePS_T2D)
PSS011747|
European Ancestry|
245,177 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Type 2 diabetes OR: 1.73 [1.69, 1.76] AUROC: 0.733 [0.728, 0.737] Age at baseline, sex assessment centre (PGS adjusted for 20 PCs prior to model fitting)
PPM021454 PGS000036
(gePS_T2D)
PSS011738|
European Ancestry|
38,941 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Incident type 2 diabetes HR: 1.63 [1.52, 1.75] C-index: 0.742 [0.725, 0.759] Age at baseline, sex (PGS adjusted for 20 PCs prior to model fitting)
PPM021464 PGS000036
(gePS_T2D)
PSS011746|
European Ancestry|
232,808 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Incident type 2 diabetes HR: 1.46 [1.42, 1.5] C-index: 0.687 [0.68, 0.693] Age at baseline, sex assessment centre (PGS adjusted for 20 PCs prior to model fitting)
PPM021482 PGS000036
(gePS_T2D)
PSS011735|
African Ancestry|
44,346 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Type 2 diabetes OR: 1.21 [1.18, 1.25] AUROC: 0.717 [0.711, 0.724] Age at baseline, sex (PGS adjusted for 20 PCs prior to model fitting)
PPM021505 PGS000036
(gePS_T2D)
PSS011736|
Hispanic or Latin American Ancestry|
33,652 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Type 2 diabetes OR: 1.41 [1.36, 1.46] AUROC: 0.759 [0.752, 0.766] Age at baseline, sex (PGS adjusted for 20 PCs prior to model fitting)
PPM021521 PGS000036
(gePS_T2D)
PSS011740|
East Asian Ancestry|
1,149 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Incident type 2 diabetes OR: 1.25 [1.07, 1.46] AUROC: 0.608 [0.566, 0.651] Age at baseline, sex (PGS adjusted for 20 PCs prior to model fitting)
PPM021547 PGS000036
(gePS_T2D)
PSS011741|
South Asian Ancestry|
852 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Incident type 2 diabetes OR: 1.23 [1.04, 1.45] AUROC: 0.651 [0.609, 0.693] Age at baseline, sex (PGS adjusted for 20 PCs prior to model fitting)
PPM021572 PGS000036
(gePS_T2D)
PSS011739|
Additional Asian Ancestries|
870 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Incident type 2 diabetes OR: 1.2 [1.01, 1.42] AUROC: 0.657 [0.612, 0.701] Age at baseline, sex (PGS adjusted for 20 PCs prior to model fitting)
PPM021591 PGS000036
(gePS_T2D)
PSS011743|
African Ancestry|
6,871 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Type 2 diabetes OR: 1.25 [1.16, 1.35] AUROC: 0.71 [0.691, 0.729] Age at baseline, sex assessment centre (PGS adjusted for 20 PCs prior to model fitting)
PPM021612 PGS000036
(gePS_T2D)
PSS011745|
East Asian Ancestry|
1,432 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Type 2 diabetes OR: 1.39 [1.1, 1.77] AUROC: 0.722 [0.668, 0.776] Age at baseline, sex assessment centre (PGS adjusted for 20 PCs prior to model fitting)
PPM021637 PGS000036
(gePS_T2D)
PSS011749|
South Asian Ancestry|
6,992 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Type 2 diabetes OR: 1.44 [1.35, 1.54] AUROC: 0.707 [0.692, 0.722] Age at baseline, sex assessment centre (PGS adjusted for 20 PCs prior to model fitting)
PPM021656 PGS000036
(gePS_T2D)
PSS011742|
African Ancestry|
6,019 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Incident type 2 diabetes HR: 1.11 [1.0, 1.22] C-index: 0.641 [0.614, 0.668] Age at baseline, sex assessment centre (PGS adjusted for 20 PCs prior to model fitting)
PPM021678 PGS000036
(gePS_T2D)
PSS011744|
East Asian Ancestry|
1,350 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Incident type 2 diabetes HR: 1.23 [0.89, 1.7] C-index: 0.68 [0.603, 0.756] Age at baseline, sex assessment centre (PGS adjusted for 20 PCs prior to model fitting)
PPM021698 PGS000036
(gePS_T2D)
PSS011748|
South Asian Ancestry|
5,685 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Incident type 2 diabetes HR: 1.15 [1.05, 1.25] C-index: 0.606 [0.583, 0.629] Age at baseline, sex assessment centre (PGS adjusted for 20 PCs prior to model fitting)
PPM000404 PGS000125
(Qi_T2D_2017)
PSS000232|
Hispanic or Latin American Ancestry|
7,746 individuals
PGP000062 |
Qi Q et al. Diabetes (2017)
Reported Trait: Type 2 Diabetes OR (Odds Ratio, per risk allele): 1.07 [1.06, 1.08] center, age, sex, 5 PCs of ancestry Covariance matrices corresponding to genetic relatedness (kinship), household, and census block group were included as random effects in the mixed model analysis
PPM000897 PGS000330
(PRS_T2D)
PSS000441|
European Ancestry|
21,030 individuals
PGP000100 |
Mars N et al. Nat Med (2020)
Reported Trait: Incident type 2 diabetes C-index: 0.845 age, sex, BMI, history of stroke or CHD, parental history of diabetes, SBP, DBP, HDL, triglycerides, FINRISK cohort, genotyping array/batch, 10 ancestry PCs 10-year risk
PPM000892 PGS000330
(PRS_T2D)
PSS000441|
European Ancestry|
21,030 individuals
PGP000100 |
Mars N et al. Nat Med (2020)
Reported Trait: Incident type 2 diabetes HR: 1.7 [1.63, 1.78] C-index: 0.763 age, sex, FINRISK cohort, genotyping array/batch, 10 ancestry PCs 10-year risk
PPM000887 PGS000330
(PRS_T2D)
PSS000448|
European Ancestry|
135,300 individuals
PGP000100 |
Mars N et al. Nat Med (2020)
Reported Trait: Type 2 diabetes (incident and prevalent cases) HR: 1.74 [1.72, 1.77] genotyping array/batch, 10 ancestry PCs, stratified by sex
PPM021416 PGS000330
(PRS_T2D)
PSS011737|
European Ancestry|
109,021 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Type 2 diabetes OR: 1.79 [1.75, 1.83] AUROC: 0.726 [0.721, 0.73] Age at baseline, sex (PGS adjusted for 20 PCs prior to model fitting)
PPM021444 PGS000330
(PRS_T2D)
PSS011738|
European Ancestry|
38,941 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Incident type 2 diabetes HR: 1.94 [1.8, 2.09] C-index: 0.767 [0.75, 0.783] Age at baseline, sex (PGS adjusted for 20 PCs prior to model fitting)
PPM021474 PGS000330
(PRS_T2D)
PSS011735|
African Ancestry|
44,346 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Type 2 diabetes OR: 1.27 [1.23, 1.31] AUROC: 0.72 [0.714, 0.727] Age at baseline, sex (PGS adjusted for 20 PCs prior to model fitting)
PPM021495 PGS000330
(PRS_T2D)
PSS011736|
Hispanic or Latin American Ancestry|
33,652 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Type 2 diabetes OR: 1.58 [1.53, 1.64] AUROC: 0.768 [0.761, 0.775] Age at baseline, sex (PGS adjusted for 20 PCs prior to model fitting)
PPM021519 PGS000330
(PRS_T2D)
PSS011740|
East Asian Ancestry|
1,149 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Incident type 2 diabetes OR: 1.29 [1.11, 1.51] AUROC: 0.619 [0.577, 0.661] Age at baseline, sex (PGS adjusted for 20 PCs prior to model fitting)
PPM021544 PGS000330
(PRS_T2D)
PSS011741|
South Asian Ancestry|
852 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Incident type 2 diabetes OR: 1.32 [1.12, 1.57] AUROC: 0.66 [0.619, 0.701] Age at baseline, sex (PGS adjusted for 20 PCs prior to model fitting)
PPM021586 PGS000330
(PRS_T2D)
PSS011743|
African Ancestry|
6,871 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Type 2 diabetes OR: 1.31 [1.21, 1.42] AUROC: 0.716 [0.696, 0.735] Age at baseline, sex assessment centre (PGS adjusted for 20 PCs prior to model fitting)
PPM021611 PGS000330
(PRS_T2D)
PSS011745|
East Asian Ancestry|
1,432 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Type 2 diabetes OR: 1.43 [1.12, 1.83] AUROC: 0.714 [0.658, 0.77] Age at baseline, sex assessment centre (PGS adjusted for 20 PCs prior to model fitting)
PPM021626 PGS000330
(PRS_T2D)
PSS011749|
South Asian Ancestry|
6,992 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Type 2 diabetes OR: 1.62 [1.51, 1.73] AUROC: 0.724 [0.709, 0.738] Age at baseline, sex assessment centre (PGS adjusted for 20 PCs prior to model fitting)
PPM021663 PGS000330
(PRS_T2D)
PSS011744|
East Asian Ancestry|
1,350 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Incident type 2 diabetes HR: 1.58 [1.13, 2.22] C-index: 0.695 [0.611, 0.779] Age at baseline, sex assessment centre (PGS adjusted for 20 PCs prior to model fitting)
PPM021687 PGS000330
(PRS_T2D)
PSS011748|
South Asian Ancestry|
5,685 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Incident type 2 diabetes HR: 1.28 [1.17, 1.4] C-index: 0.622 [0.6, 0.645] Age at baseline, sex assessment centre (PGS adjusted for 20 PCs prior to model fitting)
PPM021563 PGS000330
(PRS_T2D)
PSS011739|
Additional Asian Ancestries|
870 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Incident type 2 diabetes OR: 1.45 [1.22, 1.72] AUROC: 0.674 [0.632, 0.717] Age at baseline, sex (PGS adjusted for 20 PCs prior to model fitting)
PPM021642 PGS000330
(PRS_T2D)
PSS011742|
African Ancestry|
6,019 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Incident type 2 diabetes HR: 1.17 [1.06, 1.29] C-index: 0.646 [0.619, 0.672] Age at baseline, sex assessment centre (PGS adjusted for 20 PCs prior to model fitting)
PPM001604 PGS000712
(T2D_HbA1c_39)
PSS000755|
European Ancestry|
87,413 individuals
PGP000128 |
Sinnott-Armstrong N et al. Nat Genet (2021)
Reported Trait: Type 2 diabetes AUROC: 0.68713 Age, sex, PCs(1-10)
PPM001605 PGS000713
(T2D)
PSS000754|
European Ancestry|
87,413 individuals
PGP000128 |
Sinnott-Armstrong N et al. Nat Genet (2021)
Reported Trait: Type 2 diabetes AUROC: 0.688 Age, sex, PCs(1-10)
PPM001615 PGS000713
(T2D)
PSS000756|
European Ancestry|
135,300 individuals
PGP000128 |
Sinnott-Armstrong N et al. Nat Genet (2021)
Reported Trait: Type 2 diabetes HR: 1.49 [1.47, 1.51] C-index: 0.669 Age as time scale, sex, batch, PCs(1-10)
PPM021420 PGS000713
(T2D)
PSS011737|
European Ancestry|
109,021 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Type 2 diabetes OR: 1.63 [1.6, 1.67] AUROC: 0.712 [0.707, 0.717] Age at baseline, sex (PGS adjusted for 20 PCs prior to model fitting)
PPM021449 PGS000713
(T2D)
PSS011738|
European Ancestry|
38,941 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Incident type 2 diabetes HR: 1.74 [1.62, 1.88] C-index: 0.748 [0.732, 0.765] Age at baseline, sex (PGS adjusted for 20 PCs prior to model fitting)
PPM021479 PGS000713
(T2D)
PSS011735|
African Ancestry|
44,346 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Type 2 diabetes OR: 1.23 [1.2, 1.27] AUROC: 0.718 [0.711, 0.724] Age at baseline, sex (PGS adjusted for 20 PCs prior to model fitting)
PPM021499 PGS000713
(T2D)
PSS011736|
Hispanic or Latin American Ancestry|
33,652 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Type 2 diabetes OR: 1.46 [1.41, 1.51] AUROC: 0.762 [0.755, 0.769] Age at baseline, sex (PGS adjusted for 20 PCs prior to model fitting)
PPM021524 PGS000713
(T2D)
PSS011740|
East Asian Ancestry|
1,149 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Incident type 2 diabetes OR: 1.19 [1.02, 1.39] AUROC: 0.598 [0.554, 0.641] Age at baseline, sex (PGS adjusted for 20 PCs prior to model fitting)
PPM021550 PGS000713
(T2D)
PSS011741|
South Asian Ancestry|
852 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Incident type 2 diabetes OR: 0.91 [0.77, 1.08] AUROC: 0.643 [0.6, 0.686] Age at baseline, sex (PGS adjusted for 20 PCs prior to model fitting)
PPM021574 PGS000713
(T2D)
PSS011739|
Additional Asian Ancestries|
870 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Incident type 2 diabetes OR: 0.95 [0.8, 1.12] AUROC: 0.652 [0.608, 0.696] Age at baseline, sex (PGS adjusted for 20 PCs prior to model fitting)
PPM021587 PGS000713
(T2D)
PSS011743|
African Ancestry|
6,871 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Type 2 diabetes OR: 1.31 [1.21, 1.42] AUROC: 0.714 [0.695, 0.734] Age at baseline, sex assessment centre (PGS adjusted for 20 PCs prior to model fitting)
PPM021597 PGS000713
(T2D)
PSS011745|
East Asian Ancestry|
1,432 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Type 2 diabetes OR: 1.9 [1.48, 2.45] AUROC: 0.754 [0.7, 0.808] Age at baseline, sex assessment centre (PGS adjusted for 20 PCs prior to model fitting)
PPM021630 PGS000713
(T2D)
PSS011749|
South Asian Ancestry|
6,992 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Type 2 diabetes OR: 1.59 [1.49, 1.7] AUROC: 0.721 [0.705, 0.736] Age at baseline, sex assessment centre (PGS adjusted for 20 PCs prior to model fitting)
PPM021654 PGS000713
(T2D)
PSS011742|
African Ancestry|
6,019 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Incident type 2 diabetes HR: 1.12 [1.01, 1.23] C-index: 0.644 [0.617, 0.671] Age at baseline, sex assessment centre (PGS adjusted for 20 PCs prior to model fitting)
PPM021660 PGS000713
(T2D)
PSS011744|
East Asian Ancestry|
1,350 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Incident type 2 diabetes HR: 1.74 [1.25, 2.41] C-index: 0.722 [0.646, 0.798] Age at baseline, sex assessment centre (PGS adjusted for 20 PCs prior to model fitting)
PPM021689 PGS000713
(T2D)
PSS011748|
South Asian Ancestry|
5,685 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Incident type 2 diabetes HR: 1.26 [1.15, 1.37] C-index: 0.619 [0.596, 0.641] Age at baseline, sex assessment centre (PGS adjusted for 20 PCs prior to model fitting)
PPM001667 PGS000729
(T2D_PGS)
PSS000869|
European Ancestry|
3,087 individuals
PGP000137 |
Ritchie SC et al. Nat Metab (2021)
Reported Trait: Incident type 2 diabetes HR: 2.0 [1.36, 2.94] age, sex, 10 genetic PCs
PPM021419 PGS000729
(T2D_PGS)
PSS011737|
European Ancestry|
109,021 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Type 2 diabetes OR: 1.65 [1.61, 1.68] AUROC: 0.712 [0.707, 0.717] Age at baseline, sex (PGS adjusted for 20 PCs prior to model fitting)
PPM021448 PGS000729
(T2D_PGS)
PSS011738|
European Ancestry|
38,941 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Incident type 2 diabetes HR: 1.75 [1.62, 1.88] C-index: 0.753 [0.737, 0.77] Age at baseline, sex (PGS adjusted for 20 PCs prior to model fitting)
PPM021481 PGS000729
(T2D_PGS)
PSS011735|
African Ancestry|
44,346 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Type 2 diabetes OR: 1.23 [1.19, 1.26] AUROC: 0.718 [0.711, 0.724] Age at baseline, sex (PGS adjusted for 20 PCs prior to model fitting)
PPM021501 PGS000729
(T2D_PGS)
PSS011736|
Hispanic or Latin American Ancestry|
33,652 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Type 2 diabetes OR: 1.45 [1.4, 1.51] AUROC: 0.761 [0.754, 0.768] Age at baseline, sex (PGS adjusted for 20 PCs prior to model fitting)
PPM021522 PGS000729
(T2D_PGS)
PSS011740|
East Asian Ancestry|
1,149 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Incident type 2 diabetes OR: 1.25 [1.07, 1.46] AUROC: 0.615 [0.572, 0.657] Age at baseline, sex (PGS adjusted for 20 PCs prior to model fitting)
PPM021546 PGS000729
(T2D_PGS)
PSS011741|
South Asian Ancestry|
852 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Incident type 2 diabetes OR: 1.25 [1.06, 1.48] AUROC: 0.653 [0.612, 0.694] Age at baseline, sex (PGS adjusted for 20 PCs prior to model fitting)
PPM021565 PGS000729
(T2D_PGS)
PSS011739|
Additional Asian Ancestries|
870 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Incident type 2 diabetes OR: 1.37 [1.16, 1.63] AUROC: 0.668 [0.625, 0.712] Age at baseline, sex (PGS adjusted for 20 PCs prior to model fitting)
PPM021592 PGS000729
(T2D_PGS)
PSS011743|
African Ancestry|
6,871 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Type 2 diabetes OR: 1.25 [1.15, 1.35] AUROC: 0.711 [0.692, 0.73] Age at baseline, sex assessment centre (PGS adjusted for 20 PCs prior to model fitting)
PPM021613 PGS000729
(T2D_PGS)
PSS011745|
East Asian Ancestry|
1,432 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Type 2 diabetes OR: 1.4 [1.1, 1.8] AUROC: 0.718 [0.666, 0.771] Age at baseline, sex assessment centre (PGS adjusted for 20 PCs prior to model fitting)
PPM021632 PGS000729
(T2D_PGS)
PSS011749|
South Asian Ancestry|
6,992 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Type 2 diabetes OR: 1.55 [1.45, 1.66] AUROC: 0.717 [0.703, 0.732] Age at baseline, sex assessment centre (PGS adjusted for 20 PCs prior to model fitting)
PPM021643 PGS000729
(T2D_PGS)
PSS011742|
African Ancestry|
6,019 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Incident type 2 diabetes HR: 1.16 [1.05, 1.28] C-index: 0.642 [0.615, 0.669] Age at baseline, sex assessment centre (PGS adjusted for 20 PCs prior to model fitting)
PPM021669 PGS000729
(T2D_PGS)
PSS011744|
East Asian Ancestry|
1,350 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Incident type 2 diabetes HR: 1.4 [1.0, 1.95] C-index: 0.686 [0.611, 0.76] Age at baseline, sex assessment centre (PGS adjusted for 20 PCs prior to model fitting)
PPM021690 PGS000729
(T2D_PGS)
PSS011748|
South Asian Ancestry|
5,685 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Incident type 2 diabetes HR: 1.24 [1.14, 1.36] C-index: 0.615 [0.592, 0.638] Age at baseline, sex assessment centre (PGS adjusted for 20 PCs prior to model fitting)
PPM002117 PGS000804
(GRS582_T2Dmulti)
PSS001044|
African Ancestry|
15,609 individuals
PGP000193 |
Polfus LM et al. HGG Adv (2021)
Reported Trait: Type 2 diabetes AUROC: 0.568 [0.5588, 0.5772] Only 579 SNPs from the 582 SNP GRS, were utilised with imputation INFO scores > 0.45. 3 SNPs were not included as they were not present in the cohorts.
PPM002119 PGS000804
(GRS582_T2Dmulti)
PSS001046|
European Ancestry|
423,729 individuals
PGP000193 |
Polfus LM et al. HGG Adv (2021)
Reported Trait: Type 2 diabetes AUROC: 0.825 [0.8222, 0.8279] Odds Ratio (OR, top 10% vs middle 20%): 2.94 [2.8, 3.08] Age, sex, body mass index, PCs(1-10) Only 579 SNPs from the 582 SNP GRS, were utilised with imputation INFO scores > 0.45. 3 SNPs were not included as they were not present in the cohorts.
PPM002121 PGS000804
(GRS582_T2Dmulti)
PSS001046|
European Ancestry|
423,729 individuals
PGP000193 |
Polfus LM et al. HGG Adv (2021)
Reported Trait: Type 2 diabetes AUROC: 0.6586 [0.6547, 0.6624] Only 579 SNPs from the 582 SNP GRS, were utilised with imputation INFO scores > 0.45. 3 SNPs were not included as they were not present in the cohorts.
PPM002123 PGS000804
(GRS582_T2Dmulti)
PSS001047|
Hispanic or Latin American Ancestry|
20,486 individuals
PGP000193 |
Polfus LM et al. HGG Adv (2021)
Reported Trait: Type 2 diabetes AUROC: 0.7293 [0.721, 0.7376] Odds Ratio (OR, top 10% vs middle 20%): 2.39 [2.1, 2.73] Age, sex, body mass index, study, PCs(1-10) Only 579 SNPs from the 582 SNP GRS, were utilised with imputation INFO scores > 0.45. 3 SNPs were not included as they were not present in the cohorts.
PPM002125 PGS000804
(GRS582_T2Dmulti)
PSS001047|
Hispanic or Latin American Ancestry|
20,486 individuals
PGP000193 |
Polfus LM et al. HGG Adv (2021)
Reported Trait: Type 2 diabetes AUROC: 0.6249 [0.6156, 0.6342] Only 579 SNPs from the 582 SNP GRS, were utilised with imputation INFO scores > 0.45. 3 SNPs were not included as they were not present in the cohorts.
PPM002127 PGS000804
(GRS582_T2Dmulti)
PSS001045|
Additional Asian Ancestries|
4,576 individuals
PGP000193 |
Polfus LM et al. HGG Adv (2021)
Reported Trait: Type 2 diabetes AUROC: 0.8411 [0.8298, 0.8523] Odds Ratio (OR, top 10% vs middle 20%): 3.08 [2.4, 3.95] Age, sex, body mass index, study, PCs(1-10) Only 579 SNPs from the 582 SNP GRS, were utilised with imputation INFO scores > 0.45. 3 SNPs were not included as they were not present in the cohorts.
PPM002129 PGS000804
(GRS582_T2Dmulti)
PSS001045|
Additional Asian Ancestries|
4,576 individuals
PGP000193 |
Polfus LM et al. HGG Adv (2021)
Reported Trait: Type 2 diabetes AUROC: 0.6263 [0.6101, 0.6425] Only 579 SNPs from the 582 SNP GRS, were utilised with imputation INFO scores > 0.45. 3 SNPs were not included as they were not present in the cohorts.
PPM002131 PGS000804
(GRS582_T2Dmulti)
PSS001048|
Additional Diverse Ancestries|
3,551 individuals
PGP000193 |
Polfus LM et al. HGG Adv (2021)
Reported Trait: Type 2 diabetes AUROC: 0.7989 [0.7845, 0.8133] Odds Ratio (OR, top 10% vs middle 20%): 2.02 [1.54, 2.65] Age, sex, body mass index, PCs(1-10) Only 579 SNPs from the 582 SNP GRS, were utilised with imputation INFO scores > 0.45. 3 SNPs were not included as they were not present in the cohorts.
PPM002133 PGS000804
(GRS582_T2Dmulti)
PSS001048|
Additional Diverse Ancestries|
3,551 individuals
PGP000193 |
Polfus LM et al. HGG Adv (2021)
Reported Trait: Type 2 diabetes AUROC: 0.6214 [0.603, 0.6399] Only 579 SNPs from the 582 SNP GRS, were utilised with imputation INFO scores > 0.45. 3 SNPs were not included as they were not present in the cohorts.
PPM002115 PGS000804
(GRS582_T2Dmulti)
PSS001044|
African Ancestry|
15,609 individuals
PGP000193 |
Polfus LM et al. HGG Adv (2021)
Reported Trait: Type 2 diabetes AUROC: 0.6701 [0.6615, 0.6788] Odds Ratio (OR, top 10% vs middle 20%): 1.57 [1.39, 1.77] Age, sex, body mass index, study, PCs(1-10) Only 579 SNPs from the 582 SNP GRS, were utilised with imputation INFO scores > 0.45. 3 SNPs were not included as they were not present in the cohorts.
PPM002120 PGS000805
(GRS582_T2Deur)
PSS001046|
European Ancestry|
423,729 individuals
PGP000193 |
Polfus LM et al. HGG Adv (2021)
Reported Trait: Type 2 diabetes AUROC: 0.8253 [0.8224, 0.8281] Odds Ratio (OR, top 10% vs middle 20%): 2.95 [2.81, 3.1] Age, sex, body mass index, PCs(1-10) Only 579 SNPs from the 582 SNP GRS, were utilised with imputation INFO scores > 0.45. 3 SNPs were not included as they were not present in the cohorts.
PPM002122 PGS000805
(GRS582_T2Deur)
PSS001046|
European Ancestry|
423,729 individuals
PGP000193 |
Polfus LM et al. HGG Adv (2021)
Reported Trait: Type 2 diabetes AUROC: 0.6593 [0.6555, 0.6632] Only 579 SNPs from the 582 SNP GRS, were utilised with imputation INFO scores > 0.45. 3 SNPs were not included as they were not present in the cohorts.
PPM002134 PGS000805
(GRS582_T2Deur)
PSS001048|
Additional Diverse Ancestries|
3,551 individuals
PGP000193 |
Polfus LM et al. HGG Adv (2021)
Reported Trait: Type 2 diabetes AUROC: 0.6213 [0.6029, 0.6397] Only 579 SNPs from the 582 SNP GRS, were utilised with imputation INFO scores > 0.45. 3 SNPs were not included as they were not present in the cohorts. Population-specific weights were not available for indiviuals of an Oceanian ancestry (Native Hawaiian). Therefore, GRS582_T2Deur was utilised to predict type 2 diabetes in individuals of an Oceanian ancestry.
PPM002132 PGS000805
(GRS582_T2Deur)
PSS001048|
Additional Diverse Ancestries|
3,551 individuals
PGP000193 |
Polfus LM et al. HGG Adv (2021)
Reported Trait: Type 2 diabetes AUROC: 0.7985 [0.7842, 0.8129] Odds Ratio (OR, top 10% vs middle 20%): 2.13 [1.63, 2.79] Age, sex, body mass index, PCs(1-10) Only 579 SNPs from the 582 SNP GRS, were utilised with imputation INFO scores > 0.45. 3 SNPs were not included as they were not present in the cohorts. Population-specific weights were not available for indiviuals of an Oceanian ancestry (Native Hawaiian). Therefore, GRS582_T2Deur was utilised to predict type 2 diabetes in individuals of an Oceanian ancestry.
PPM021422 PGS000805
(GRS582_T2Deur)
PSS011737|
European Ancestry|
109,021 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Type 2 diabetes OR: 1.59 [1.56, 1.63] AUROC: 0.707 [0.702, 0.712] Age at baseline, sex (PGS adjusted for 20 PCs prior to model fitting)
PPM021457 PGS000805
(GRS582_T2Deur)
PSS011738|
European Ancestry|
38,941 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Incident type 2 diabetes HR: 1.59 [1.48, 1.71] C-index: 0.736 [0.718, 0.753] Age at baseline, sex (PGS adjusted for 20 PCs prior to model fitting)
PPM021477 PGS000805
(GRS582_T2Deur)
PSS011735|
African Ancestry|
44,346 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Type 2 diabetes OR: 1.23 [1.2, 1.27] AUROC: 0.718 [0.711, 0.724] Age at baseline, sex (PGS adjusted for 20 PCs prior to model fitting)
PPM021497 PGS000805
(GRS582_T2Deur)
PSS011736|
Hispanic or Latin American Ancestry|
33,652 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Type 2 diabetes OR: 1.49 [1.44, 1.55] AUROC: 0.764 [0.758, 0.771] Age at baseline, sex (PGS adjusted for 20 PCs prior to model fitting)
PPM021518 PGS000805
(GRS582_T2Deur)
PSS011740|
East Asian Ancestry|
1,149 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Incident type 2 diabetes OR: 1.3 [1.11, 1.52] AUROC: 0.613 [0.572, 0.654] Age at baseline, sex (PGS adjusted for 20 PCs prior to model fitting)
PPM021561 PGS000805
(GRS582_T2Deur)
PSS011739|
Additional Asian Ancestries|
870 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Incident type 2 diabetes OR: 1.58 [1.33, 1.88] AUROC: 0.701 [0.659, 0.743] Age at baseline, sex (PGS adjusted for 20 PCs prior to model fitting)
PPM021590 PGS000805
(GRS582_T2Deur)
PSS011743|
African Ancestry|
6,871 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Type 2 diabetes OR: 1.27 [1.18, 1.38] AUROC: 0.714 [0.694, 0.733] Age at baseline, sex assessment centre (PGS adjusted for 20 PCs prior to model fitting)
PPM021603 PGS000805
(GRS582_T2Deur)
PSS011745|
East Asian Ancestry|
1,432 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Type 2 diabetes OR: 1.7 [1.35, 2.16] AUROC: 0.734 [0.679, 0.788] Age at baseline, sex assessment centre (PGS adjusted for 20 PCs prior to model fitting)
PPM021629 PGS000805
(GRS582_T2Deur)
PSS011749|
South Asian Ancestry|
6,992 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Type 2 diabetes OR: 1.61 [1.51, 1.73] AUROC: 0.721 [0.706, 0.736] Age at baseline, sex assessment centre (PGS adjusted for 20 PCs prior to model fitting)
PPM021640 PGS000805
(GRS582_T2Deur)
PSS011742|
African Ancestry|
6,019 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Incident type 2 diabetes HR: 1.19 [1.08, 1.31] C-index: 0.646 [0.619, 0.673] Age at baseline, sex assessment centre (PGS adjusted for 20 PCs prior to model fitting)
PPM021673 PGS000805
(GRS582_T2Deur)
PSS011744|
East Asian Ancestry|
1,350 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Incident type 2 diabetes HR: 1.28 [0.93, 1.76] C-index: 0.679 [0.606, 0.753] Age at baseline, sex assessment centre (PGS adjusted for 20 PCs prior to model fitting)
PPM021688 PGS000805
(GRS582_T2Deur)
PSS011748|
South Asian Ancestry|
5,685 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Incident type 2 diabetes HR: 1.26 [1.16, 1.38] C-index: 0.617 [0.594, 0.64] Age at baseline, sex assessment centre (PGS adjusted for 20 PCs prior to model fitting)
PPM021537 PGS000805
(GRS582_T2Deur)
PSS011741|
South Asian Ancestry|
852 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Incident type 2 diabetes OR: 1.45 [1.23, 1.72] AUROC: 0.674 [0.633, 0.716] Age at baseline, sex (PGS adjusted for 20 PCs prior to model fitting)
PPM002116 PGS000806
(GRS582_T2Dafr)
PSS001044|
African Ancestry|
15,609 individuals
PGP000193 |
Polfus LM et al. HGG Adv (2021)
Reported Trait: Type 2 diabetes AUROC: 0.6656 [0.6569, 0.6743] Odds Ratio (OR, top 10% vs middle 20%): 1.53 [1.36, 1.73] Age, sex, body mass index, study, PCs(1-10) Only 579 SNPs from the 582 SNP GRS, were utilised with imputation INFO scores > 0.45. 3 SNPs were not included as they were not present in the cohorts.
PPM002118 PGS000806
(GRS582_T2Dafr)
PSS001044|
African Ancestry|
15,609 individuals
PGP000193 |
Polfus LM et al. HGG Adv (2021)
Reported Trait: Type 2 diabetes AUROC: 0.5592 [0.5499, 0.5684] Only 579 SNPs from the 582 SNP GRS, were utilised with imputation INFO scores > 0.45. 3 SNPs were not included as they were not present in the cohorts.
PPM002128 PGS000807
(GRS582_T2Dasn)
PSS001045|
Additional Asian Ancestries|
4,576 individuals
PGP000193 |
Polfus LM et al. HGG Adv (2021)
Reported Trait: Type 2 diabetes AUROC: 0.8388 [0.8274, 0.8502] Odds Ratio (OR, top 10% vs middle 20%): 2.84 [2.21, 3.65] Age, sex, body mass index, study, PCs(1-10) Only 579 SNPs from the 582 SNP GRS, were utilised with imputation INFO scores > 0.45. 3 SNPs were not included as they were not present in the cohorts.
PPM002130 PGS000807
(GRS582_T2Dasn)
PSS001045|
Additional Asian Ancestries|
4,576 individuals
PGP000193 |
Polfus LM et al. HGG Adv (2021)
Reported Trait: Type 2 diabetes AUROC: 0.6161 [0.5998, 0.6324] Only 579 SNPs from the 582 SNP GRS, were utilised with imputation INFO scores > 0.45. 3 SNPs were not included as they were not present in the cohorts.
PPM002135 PGS000807
(GRS582_T2Dasn)
PSS001048|
Additional Diverse Ancestries|
3,551 individuals
PGP000193 |
Polfus LM et al. HGG Adv (2021)
Reported Trait: Type 2 diabetes AUROC: 0.7909 [0.7763, 0.8056] Odds Ratio (OR, top 10% vs middle 20%): 1.62 [1.23, 2.14] Age, sex, body mass index, PCs(1-10) Only 579 SNPs from the 582 SNP GRS, were utilised with imputation INFO scores > 0.45. 3 SNPs were not included as they were not present in the cohorts. Population-specific weights were not available for indiviuals of an Oceanian ancestry (Native Hawaiian). Therefore, GRS582_T2Dasn was utilised to predict type 2 diabetes in individuals of an Oceanian ancestry.
PPM002136 PGS000807
(GRS582_T2Dasn)
PSS001048|
Additional Diverse Ancestries|
3,551 individuals
PGP000193 |
Polfus LM et al. HGG Adv (2021)
Reported Trait: Type 2 diabetes AUROC: 0.5768 [0.558, 0.5956] Only 579 SNPs from the 582 SNP GRS, were utilised with imputation INFO scores > 0.45. 3 SNPs were not included as they were not present in the cohorts. Population-specific weights were not available for indiviuals of an Oceanian ancestry (Native Hawaiian). Therefore, GRS582_T2Dasn was utilised to predict type 2 diabetes in individuals of an Oceanian ancestry.
PPM002124 PGS000808
(GRS582_T2Dhis)
PSS001047|
Hispanic or Latin American Ancestry|
20,486 individuals
PGP000193 |
Polfus LM et al. HGG Adv (2021)
Reported Trait: Type 2 diabetes AUROC: 0.7202 [0.7118, 0.7286] Odds Ratio (OR, top 10% vs middle 20%): 2.04 [1.79, 2.32] Age, sex, body mass index, study, PCs(1-10) Only 579 SNPs from the 582 SNP GRS, were utilised with imputation INFO scores > 0.45. 3 SNPs were not included as they were not present in the cohorts.
PPM002126 PGS000808
(GRS582_T2Dhis)
PSS001047|
Hispanic or Latin American Ancestry|
20,486 individuals
PGP000193 |
Polfus LM et al. HGG Adv (2021)
Reported Trait: Type 2 diabetes AUROC: 0.6098 [0.6004, 0.6192] Only 579 SNPs from the 582 SNP GRS, were utilised with imputation INFO scores > 0.45. 3 SNPs were not included as they were not present in the cohorts.
PPM002240 PGS000832
(T2D-GRS)
PSS001088|
European Ancestry|
3,869 individuals
PGP000211 |
Aly DM et al. Nat Genet (2021)
Reported Trait: Severe Insulin-Resistant Diabetes OR: 1.24 [1.16, 1.34] PC1-10
PPM002242 PGS000832
(T2D-GRS)
PSS001084|
European Ancestry|
5,597 individuals
PGP000211 |
Aly DM et al. Nat Genet (2021)
Reported Trait: Moderate Age-Related Diabetes OR: 1.77 [1.67, 1.88] PC1-10
PPM002239 PGS000832
(T2D-GRS)
PSS001087|
European Ancestry|
3,930 individuals
PGP000211 |
Aly DM et al. Nat Genet (2021)
Reported Trait: Severe Insulin-Deficient Diabetes OR: 1.96 [1.81, 2.12] PC1-10
PPM002238 PGS000832
(T2D-GRS)
PSS001086|
European Ancestry|
3,194 individuals
PGP000211 |
Aly DM et al. Nat Genet (2021)
Reported Trait: Severe Autoimmune Diabetes OR: 1.28 [1.16, 1.42] PC1-10
PPM002241 PGS000832
(T2D-GRS)
PSS001085|
European Ancestry|
4,116 individuals
PGP000211 |
Aly DM et al. Nat Genet (2021)
Reported Trait: Moderate Obesity-related Diabetes OR: 1.73 [1.61, 1.86] PC1-10
PPM020163 PGS000832
(T2D-GRS)
PSS011301|
South Asian Ancestry|
1,282 individuals
PGP000525 |
Yajnik CS et al. Lancet Reg Health Southeast Asia (2023)
|Ext.
Reported Trait: Type 2 diabetes OR: 1.78 [1.49, 2.13] age, sex and BMI Evaluated on 381 of 384 SNPs based on the availability of variants in the cohort
PPM020196 PGS000832
(T2D-GRS)
PSS011303|
South Asian Ancestry|
729 individuals
PGP000525 |
Yajnik CS et al. Lancet Reg Health Southeast Asia (2023)
|Ext.
Reported Trait: Mild obesity-related diabetes OR: 1.5 [1.27, 1.76] sex Evaluated on 381 of 384 SNPs based on the availability of variants in the cohort
PPM020207 PGS000832
(T2D-GRS)
PSS011305|
South Asian Ancestry|
624 individuals
PGP000525 |
Yajnik CS et al. Lancet Reg Health Southeast Asia (2023)
|Ext.
Reported Trait: Mild age-related diabetes OR: 1.54 [1.27, 1.87] sex Evaluated on 381 of 384 SNPs based on the availability of variants in the cohort
PPM020184 PGS000832
(T2D-GRS)
PSS011302|
South Asian Ancestry|
830 individuals
PGP000525 |
Yajnik CS et al. Lancet Reg Health Southeast Asia (2023)
|Ext.
Reported Trait: Severe insulin deficiency diabetes OR: 1.66 [1.42, 1.93] sex Evaluated on 381 of 384 SNPs based on the availability of variants in the cohort
PPM002243 PGS000833
(T1D)
PSS001086|
European Ancestry|
3,194 individuals
PGP000211 |
Aly DM et al. Nat Genet (2021)
Reported Trait: Severe Autoimmune Diabetes OR: 1.39 [1.25, 1.54] PC1-10
PPM002246 PGS000833
(T1D)
PSS001085|
European Ancestry|
4,116 individuals
PGP000211 |
Aly DM et al. Nat Genet (2021)
Reported Trait: Moderate Obesity-related Diabetes OR: 1.04 [0.97, 1.11] PC1-10
PPM002247 PGS000833
(T1D)
PSS001084|
European Ancestry|
5,597 individuals
PGP000211 |
Aly DM et al. Nat Genet (2021)
Reported Trait: Moderate Age-Related Diabetes OR: 1.02 [0.97, 1.07] PC1-10
PPM002244 PGS000833
(T1D)
PSS001087|
European Ancestry|
3,930 individuals
PGP000211 |
Aly DM et al. Nat Genet (2021)
Reported Trait: Severe Insulin-Deficient Diabetes OR: 1.01 [0.94, 1.08] PC1-10
PPM002245 PGS000833
(T1D)
PSS001088|
European Ancestry|
3,869 individuals
PGP000211 |
Aly DM et al. Nat Genet (2021)
Reported Trait: Severe Insulin-Resistant Diabetes OR: 1.03 [0.96, 1.11] PC1-10
PPM002323 PGS000848
(T2D_Adiposity)
PSS001086|
European Ancestry|
3,194 individuals
PGP000211 |
Aly DM et al. Nat Genet (2021)
Reported Trait: Severe Autoimmune Diabetes OR: 1.11 [1.0, 1.23] PC1-10
PPM002324 PGS000848
(T2D_Adiposity)
PSS001087|
European Ancestry|
3,930 individuals
PGP000211 |
Aly DM et al. Nat Genet (2021)
Reported Trait: Severe Insulin-Deficient Diabetes OR: 1.1 [1.02, 1.18] PC1-10
PPM002325 PGS000848
(T2D_Adiposity)
PSS001088|
European Ancestry|
3,869 individuals
PGP000211 |
Aly DM et al. Nat Genet (2021)
Reported Trait: Severe Insulin-Resistant Diabetes OR: 1.11 [1.03, 1.19] PC1-10
PPM002326 PGS000848
(T2D_Adiposity)
PSS001085|
European Ancestry|
4,116 individuals
PGP000211 |
Aly DM et al. Nat Genet (2021)
Reported Trait: Moderate Obesity-related Diabetes OR: 1.2 [1.12, 1.28] PC1-10
PPM002327 PGS000848
(T2D_Adiposity)
PSS001084|
European Ancestry|
5,597 individuals
PGP000211 |
Aly DM et al. Nat Genet (2021)
Reported Trait: Moderate Age-Related Diabetes OR: 1.06 [1.0, 1.12] PC1-10
PPM020167 PGS000848
(T2D_Adiposity)
PSS011301|
South Asian Ancestry|
1,282 individuals
PGP000525 |
Yajnik CS et al. Lancet Reg Health Southeast Asia (2023)
|Ext.
Reported Trait: Type 2 diabetes OR: 1.14 [1.01, 1.28] sex
PPM020183 PGS000848
(T2D_Adiposity)
PSS011301|
South Asian Ancestry|
1,282 individuals
PGP000525 |
Yajnik CS et al. Lancet Reg Health Southeast Asia (2023)
|Ext.
Reported Trait: BMI β: 0.06772 (0.027943)
PPM020187 PGS000848
(T2D_Adiposity)
PSS011302|
South Asian Ancestry|
830 individuals
PGP000525 |
Yajnik CS et al. Lancet Reg Health Southeast Asia (2023)
|Ext.
Reported Trait: Severe insulin deficiency diabetes OR: 1.23 [1.07, 1.43] sex
PPM002329 PGS000849
(T2D_Impaired_Lipids)
PSS001087|
European Ancestry|
3,930 individuals
PGP000211 |
Aly DM et al. Nat Genet (2021)
Reported Trait: Severe Insulin-Deficient Diabetes OR: 1.07 [1.0, 1.15] PC1-10
PPM002330 PGS000849
(T2D_Impaired_Lipids)
PSS001088|
European Ancestry|
3,869 individuals
PGP000211 |
Aly DM et al. Nat Genet (2021)
Reported Trait: Severe Insulin-Resistant Diabetes OR: 1.09 [1.01, 1.17] PC1-10
PPM002331 PGS000849
(T2D_Impaired_Lipids)
PSS001085|
European Ancestry|
4,116 individuals
PGP000211 |
Aly DM et al. Nat Genet (2021)
Reported Trait: Moderate Obesity-related Diabetes OR: 1.0 [0.93, 1.07] PC1-10
PPM002332 PGS000849
(T2D_Impaired_Lipids)
PSS001084|
European Ancestry|
5,597 individuals
PGP000211 |
Aly DM et al. Nat Genet (2021)
Reported Trait: Moderate Age-Related Diabetes OR: 1.06 [1.0, 1.12] PC1-10
PPM002328 PGS000849
(T2D_Impaired_Lipids)
PSS001086|
European Ancestry|
3,194 individuals
PGP000211 |
Aly DM et al. Nat Genet (2021)
Reported Trait: Severe Autoimmune Diabetes OR: 1.08 [0.97, 1.2] PC1-10
PPM020176 PGS000849
(T2D_Impaired_Lipids)
PSS011301|
South Asian Ancestry|
1,282 individuals
PGP000525 |
Yajnik CS et al. Lancet Reg Health Southeast Asia (2023)
|Ext.
Reported Trait: Type 2 diabetes OR: 1.2 [1.0, 1.44] age, sex and BMI
PPM020194 PGS000849
(T2D_Impaired_Lipids)
PSS011302|
South Asian Ancestry|
830 individuals
PGP000525 |
Yajnik CS et al. Lancet Reg Health Southeast Asia (2023)
|Ext.
Reported Trait: Severe insulin deficiency diabetes OR: 1.2 [1.03, 1.4] sex
PPM020204 PGS000849
(T2D_Impaired_Lipids)
PSS011303|
South Asian Ancestry|
729 individuals
PGP000525 |
Yajnik CS et al. Lancet Reg Health Southeast Asia (2023)
|Ext.
Reported Trait: Mild obesity-related diabetes OR: 1.26 [1.07, 1.49] sex
PPM002333 PGS000850
(T2D_Insulin_Action)
PSS001086|
European Ancestry|
3,194 individuals
PGP000211 |
Aly DM et al. Nat Genet (2021)
Reported Trait: Severe Autoimmune Diabetes OR: 1.08 [0.98, 1.2] PC1-10
PPM002334 PGS000850
(T2D_Insulin_Action)
PSS001087|
European Ancestry|
3,930 individuals
PGP000211 |
Aly DM et al. Nat Genet (2021)
Reported Trait: Severe Insulin-Deficient Diabetes OR: 1.17 [1.09, 1.25] PC1-10
PPM002335 PGS000850
(T2D_Insulin_Action)
PSS001088|
European Ancestry|
3,869 individuals
PGP000211 |
Aly DM et al. Nat Genet (2021)
Reported Trait: Severe Insulin-Resistant Diabetes OR: 1.17 [1.09, 1.26] PC1-10
PPM002337 PGS000850
(T2D_Insulin_Action)
PSS001084|
European Ancestry|
5,597 individuals
PGP000211 |
Aly DM et al. Nat Genet (2021)
Reported Trait: Moderate Age-Related Diabetes OR: 1.16 [1.1, 1.23] PC1-10
PPM002336 PGS000850
(T2D_Insulin_Action)
PSS001085|
European Ancestry|
4,116 individuals
PGP000211 |
Aly DM et al. Nat Genet (2021)
Reported Trait: Moderate Obesity-related Diabetes OR: 1.14 [1.07, 1.22] PC1-10
PPM020173 PGS000850
(T2D_Insulin_Action)
PSS011301|
South Asian Ancestry|
1,282 individuals
PGP000525 |
Yajnik CS et al. Lancet Reg Health Southeast Asia (2023)
|Ext.
Reported Trait: Type 2 diabetes OR: 1.16 [1.03, 1.3] sex
PPM020201 PGS000850
(T2D_Insulin_Action)
PSS011303|
South Asian Ancestry|
729 individuals
PGP000525 |
Yajnik CS et al. Lancet Reg Health Southeast Asia (2023)
|Ext.
Reported Trait: Mild obesity-related diabetes OR: 1.17 [1.0, 1.36] sex
PPM020213 PGS000850
(T2D_Insulin_Action)
PSS011305|
South Asian Ancestry|
624 individuals
PGP000525 |
Yajnik CS et al. Lancet Reg Health Southeast Asia (2023)
|Ext.
Reported Trait: Mild age-related diabetes OR: 1.26 [1.04, 1.53] sex
PPM002338 PGS000851
(T2D_Insulin_Action_Secretion)
PSS001086|
European Ancestry|
3,194 individuals
PGP000211 |
Aly DM et al. Nat Genet (2021)
Reported Trait: Severe Autoimmune Diabetes OR: 1.24 [1.12, 1.37] PC1-10
PPM002339 PGS000851
(T2D_Insulin_Action_Secretion)
PSS001087|
European Ancestry|
3,930 individuals
PGP000211 |
Aly DM et al. Nat Genet (2021)
Reported Trait: Severe Insulin-Deficient Diabetes OR: 1.23 [1.15, 1.32] PC1-10
PPM002340 PGS000851
(T2D_Insulin_Action_Secretion)
PSS001088|
European Ancestry|
3,869 individuals
PGP000211 |
Aly DM et al. Nat Genet (2021)
Reported Trait: Severe Insulin-Resistant Diabetes OR: 1.04 [0.97, 1.11] PC1-10
PPM002341 PGS000851
(T2D_Insulin_Action_Secretion)
PSS001085|
European Ancestry|
4,116 individuals
PGP000211 |
Aly DM et al. Nat Genet (2021)
Reported Trait: Moderate Obesity-related Diabetes OR: 1.19 [1.12, 1.28] PC1-10
PPM002342 PGS000851
(T2D_Insulin_Action_Secretion)
PSS001084|
European Ancestry|
5,597 individuals
PGP000211 |
Aly DM et al. Nat Genet (2021)
Reported Trait: Moderate Age-Related Diabetes OR: 1.19 [1.13, 1.26] PC1-10
PPM020172 PGS000851
(T2D_Insulin_Action_Secretion)
PSS011301|
South Asian Ancestry|
1,282 individuals
PGP000525 |
Yajnik CS et al. Lancet Reg Health Southeast Asia (2023)
|Ext.
Reported Trait: Type 2 diabetes OR: 1.07 [0.9, 1.28] age, sex and BMI
PPM020192 PGS000851
(T2D_Insulin_Action_Secretion)
PSS011302|
South Asian Ancestry|
830 individuals
PGP000525 |
Yajnik CS et al. Lancet Reg Health Southeast Asia (2023)
|Ext.
Reported Trait: Severe insulin deficiency diabetes OR: 1.17 [1.01, 1.34] sex
PPM020212 PGS000851
(T2D_Insulin_Action_Secretion)
PSS011305|
South Asian Ancestry|
624 individuals
PGP000525 |
Yajnik CS et al. Lancet Reg Health Southeast Asia (2023)
|Ext.
Reported Trait: Mild age-related diabetes OR: 1.45 [1.19, 1.78] sex
PPM002343 PGS000852
(T2D_Insulin_Secretion_1)
PSS001086|
European Ancestry|
3,194 individuals
PGP000211 |
Aly DM et al. Nat Genet (2021)
Reported Trait: Severe Autoimmune Diabetes OR: 1.01 [0.91, 1.12] PC1-10
PPM002344 PGS000852
(T2D_Insulin_Secretion_1)
PSS001087|
European Ancestry|
3,930 individuals
PGP000211 |
Aly DM et al. Nat Genet (2021)
Reported Trait: Severe Insulin-Deficient Diabetes OR: 1.31 [1.22, 1.41] PC1-10
PPM002345 PGS000852
(T2D_Insulin_Secretion_1)
PSS001088|
European Ancestry|
3,869 individuals
PGP000211 |
Aly DM et al. Nat Genet (2021)
Reported Trait: Severe Insulin-Resistant Diabetes OR: 1.04 [0.97, 1.12] PC1-10
PPM002347 PGS000852
(T2D_Insulin_Secretion_1)
PSS001084|
European Ancestry|
5,597 individuals
PGP000211 |
Aly DM et al. Nat Genet (2021)
Reported Trait: Moderate Age-Related Diabetes OR: 1.29 [1.22, 1.37] PC1-10
PPM002346 PGS000852
(T2D_Insulin_Secretion_1)
PSS001085|
European Ancestry|
4,116 individuals
PGP000211 |
Aly DM et al. Nat Genet (2021)
Reported Trait: Moderate Obesity-related Diabetes OR: 1.26 [1.18, 1.35] PC1-10
PPM020170 PGS000852
(T2D_Insulin_Secretion_1)
PSS011301|
South Asian Ancestry|
1,282 individuals
PGP000525 |
Yajnik CS et al. Lancet Reg Health Southeast Asia (2023)
|Ext.
Reported Trait: Type 2 diabetes OR: 1.33 [1.12, 1.58] age, sex and BMI
PPM020190 PGS000852
(T2D_Insulin_Secretion_1)
PSS011302|
South Asian Ancestry|
830 individuals
PGP000525 |
Yajnik CS et al. Lancet Reg Health Southeast Asia (2023)
|Ext.
Reported Trait: Severe insulin deficiency diabetes OR: 1.38 [1.19, 1.59] sex
PPM020199 PGS000852
(T2D_Insulin_Secretion_1)
PSS011303|
South Asian Ancestry|
729 individuals
PGP000525 |
Yajnik CS et al. Lancet Reg Health Southeast Asia (2023)
|Ext.
Reported Trait: Mild obesity-related diabetes OR: 1.25 [1.08, 1.46] sex
PPM020210 PGS000852
(T2D_Insulin_Secretion_1)
PSS011305|
South Asian Ancestry|
624 individuals
PGP000525 |
Yajnik CS et al. Lancet Reg Health Southeast Asia (2023)
|Ext.
Reported Trait: Mild age-related diabetes OR: 1.33 [1.1, 1.61] sex
PPM002348 PGS000853
(T2D_Insulin_Secretion_2)
PSS001086|
European Ancestry|
3,194 individuals
PGP000211 |
Aly DM et al. Nat Genet (2021)
Reported Trait: Severe Autoimmune Diabetes OR: 0.99 [0.9, 1.1] PC1-10
PPM002349 PGS000853
(T2D_Insulin_Secretion_2)
PSS001087|
European Ancestry|
3,930 individuals
PGP000211 |
Aly DM et al. Nat Genet (2021)
Reported Trait: Severe Insulin-Deficient Diabetes OR: 1.26 [1.18, 1.36] PC1-10
PPM002350 PGS000853
(T2D_Insulin_Secretion_2)
PSS001088|
European Ancestry|
3,869 individuals
PGP000211 |
Aly DM et al. Nat Genet (2021)
Reported Trait: Severe Insulin-Resistant Diabetes OR: 1.02 [0.95, 1.09] PC1-10
PPM002351 PGS000853
(T2D_Insulin_Secretion_2)
PSS001085|
European Ancestry|
4,116 individuals
PGP000211 |
Aly DM et al. Nat Genet (2021)
Reported Trait: Moderate Obesity-related Diabetes OR: 1.18 [1.11, 1.27] PC1-10
PPM002352 PGS000853
(T2D_Insulin_Secretion_2)
PSS001084|
European Ancestry|
5,597 individuals
PGP000211 |
Aly DM et al. Nat Genet (2021)
Reported Trait: Moderate Age-Related Diabetes OR: 1.23 [1.17, 1.3] PC1-10
PPM020171 PGS000853
(T2D_Insulin_Secretion_2)
PSS011301|
South Asian Ancestry|
1,282 individuals
PGP000525 |
Yajnik CS et al. Lancet Reg Health Southeast Asia (2023)
|Ext.
Reported Trait: Type 2 diabetes OR: 1.32 [1.11, 1.57] age, sex and BMI
PPM020200 PGS000853
(T2D_Insulin_Secretion_2)
PSS011303|
South Asian Ancestry|
729 individuals
PGP000525 |
Yajnik CS et al. Lancet Reg Health Southeast Asia (2023)
|Ext.
Reported Trait: Mild obesity-related diabetes OR: 1.24 [1.07, 1.45] sex
PPM020211 PGS000853
(T2D_Insulin_Secretion_2)
PSS011305|
South Asian Ancestry|
624 individuals
PGP000525 |
Yajnik CS et al. Lancet Reg Health Southeast Asia (2023)
|Ext.
Reported Trait: Mild age-related diabetes OR: 1.32 [1.1, 1.59] sex
PPM002353 PGS000854
(T2D_BetaCell)
PSS001086|
European Ancestry|
3,194 individuals
PGP000211 |
Aly DM et al. Nat Genet (2021)
Reported Trait: Severe Autoimmune Diabetes OR: 1.0 [0.91, 1.11] PC1-10
PPM002354 PGS000854
(T2D_BetaCell)
PSS001087|
European Ancestry|
3,930 individuals
PGP000211 |
Aly DM et al. Nat Genet (2021)
Reported Trait: Severe Insulin-Deficient Diabetes OR: 1.32 [1.23, 1.42] PC1-10
PPM002355 PGS000854
(T2D_BetaCell)
PSS001088|
European Ancestry|
3,869 individuals
PGP000211 |
Aly DM et al. Nat Genet (2021)
Reported Trait: Severe Insulin-Resistant Diabetes OR: 1.01 [0.94, 1.08] PC1-10
PPM002357 PGS000854
(T2D_BetaCell)
PSS001084|
European Ancestry|
5,597 individuals
PGP000211 |
Aly DM et al. Nat Genet (2021)
Reported Trait: Moderate Age-Related Diabetes OR: 1.27 [1.2, 1.34] PC1-10
PPM002356 PGS000854
(T2D_BetaCell)
PSS001085|
European Ancestry|
4,116 individuals
PGP000211 |
Aly DM et al. Nat Genet (2021)
Reported Trait: Moderate Obesity-related Diabetes OR: 1.21 [1.13, 1.3] PC1-10
PPM020168 PGS000854
(T2D_BetaCell)
PSS011301|
South Asian Ancestry|
1,282 individuals
PGP000525 |
Yajnik CS et al. Lancet Reg Health Southeast Asia (2023)
|Ext.
Reported Trait: Type 2 diabetes OR: 0.89 [0.79, 1.0] sex
PPM020188 PGS000854
(T2D_BetaCell)
PSS011302|
South Asian Ancestry|
830 individuals
PGP000525 |
Yajnik CS et al. Lancet Reg Health Southeast Asia (2023)
|Ext.
Reported Trait: Severe insulin deficiency diabetes OR: 0.87 [0.75, 1.0] sex
PPM020209 PGS000854
(T2D_BetaCell)
PSS011305|
South Asian Ancestry|
624 individuals
PGP000525 |
Yajnik CS et al. Lancet Reg Health Southeast Asia (2023)
|Ext.
Reported Trait: Mild age-related diabetes OR: 0.81 [0.67, 0.97] sex
PPM002358 PGS000855
(T2D_Lipodystrophy)
PSS001086|
European Ancestry|
3,194 individuals
PGP000211 |
Aly DM et al. Nat Genet (2021)
Reported Trait: Severe Autoimmune Diabetes OR: 1.12 [1.01, 1.25] PC1-10
PPM002359 PGS000855
(T2D_Lipodystrophy)
PSS001087|
European Ancestry|
3,930 individuals
PGP000211 |
Aly DM et al. Nat Genet (2021)
Reported Trait: Severe Insulin-Deficient Diabetes OR: 1.23 [1.15, 1.33] PC1-10
PPM002360 PGS000855
(T2D_Lipodystrophy)
PSS001088|
European Ancestry|
3,869 individuals
PGP000211 |
Aly DM et al. Nat Genet (2021)
Reported Trait: Severe Insulin-Resistant Diabetes OR: 1.15 [1.07, 1.24] PC1-10
PPM002361 PGS000855
(T2D_Lipodystrophy)
PSS001085|
European Ancestry|
4,116 individuals
PGP000211 |
Aly DM et al. Nat Genet (2021)
Reported Trait: Moderate Obesity-related Diabetes OR: 1.14 [1.06, 1.22] PC1-10
PPM002362 PGS000855
(T2D_Lipodystrophy)
PSS001084|
European Ancestry|
5,597 individuals
PGP000211 |
Aly DM et al. Nat Genet (2021)
Reported Trait: Moderate Age-Related Diabetes OR: 1.18 [1.11, 1.24] PC1-10
PPM020175 PGS000855
(T2D_Lipodystrophy)
PSS011301|
South Asian Ancestry|
1,282 individuals
PGP000525 |
Yajnik CS et al. Lancet Reg Health Southeast Asia (2023)
|Ext.
Reported Trait: Type 2 diabetes OR: 1.17 [1.04, 1.31] sex
PPM020193 PGS000855
(T2D_Lipodystrophy)
PSS011302|
South Asian Ancestry|
830 individuals
PGP000525 |
Yajnik CS et al. Lancet Reg Health Southeast Asia (2023)
|Ext.
Reported Trait: Severe insulin deficiency diabetes OR: 1.16 [1.0, 1.34] sex
PPM020203 PGS000855
(T2D_Lipodystrophy)
PSS011303|
South Asian Ancestry|
729 individuals
PGP000525 |
Yajnik CS et al. Lancet Reg Health Southeast Asia (2023)
|Ext.
Reported Trait: Mild obesity-related diabetes OR: 1.18 [1.01, 1.37] sex
PPM002363 PGS000856
(T2D_LiverLipids)
PSS001086|
European Ancestry|
3,194 individuals
PGP000211 |
Aly DM et al. Nat Genet (2021)
Reported Trait: Severe Autoimmune Diabetes OR: 1.35 [1.22, 1.51] PC1-10
PPM002364 PGS000856
(T2D_LiverLipids)
PSS001087|
European Ancestry|
3,930 individuals
PGP000211 |
Aly DM et al. Nat Genet (2021)
Reported Trait: Severe Insulin-Deficient Diabetes OR: 1.01 [0.94, 1.08] PC1-10
PPM002366 PGS000856
(T2D_LiverLipids)
PSS001085|
European Ancestry|
4,116 individuals
PGP000211 |
Aly DM et al. Nat Genet (2021)
Reported Trait: Moderate Obesity-related Diabetes OR: 1.02 [0.95, 1.09] PC1-10
PPM002367 PGS000856
(T2D_LiverLipids)
PSS001084|
European Ancestry|
5,597 individuals
PGP000211 |
Aly DM et al. Nat Genet (2021)
Reported Trait: Moderate Age-Related Diabetes OR: 0.95 [0.9, 1.01] PC1-10
PPM002365 PGS000856
(T2D_LiverLipids)
PSS001088|
European Ancestry|
3,869 individuals
PGP000211 |
Aly DM et al. Nat Genet (2021)
Reported Trait: Severe Insulin-Resistant Diabetes OR: 0.97 [0.91, 1.05] PC1-10
PPM020177 PGS000856
(T2D_LiverLipids)
PSS011301|
South Asian Ancestry|
1,282 individuals
PGP000525 |
Yajnik CS et al. Lancet Reg Health Southeast Asia (2023)
|Ext.
Reported Trait: Type 2 diabetes OR: 1.29 [1.09, 1.54] age, sex and BMI
PPM020195 PGS000856
(T2D_LiverLipids)
PSS011302|
South Asian Ancestry|
830 individuals
PGP000525 |
Yajnik CS et al. Lancet Reg Health Southeast Asia (2023)
|Ext.
Reported Trait: Severe insulin deficiency diabetes OR: 1.24 [1.07, 1.43] sex
PPM020205 PGS000856
(T2D_LiverLipids)
PSS011303|
South Asian Ancestry|
729 individuals
PGP000525 |
Yajnik CS et al. Lancet Reg Health Southeast Asia (2023)
|Ext.
Reported Trait: Mild obesity-related diabetes OR: 1.31 [1.12, 1.53] sex
PPM020206 PGS000856
(T2D_LiverLipids)
PSS011304|
South Asian Ancestry|
482 individuals
PGP000525 |
Yajnik CS et al. Lancet Reg Health Southeast Asia (2023)
|Ext.
Reported Trait: Severe insulin-resistant diabetes OR: 2.04 [1.26, 3.3] sex
PPM002368 PGS000857
(T2D_Obesity)
PSS001086|
European Ancestry|
3,194 individuals
PGP000211 |
Aly DM et al. Nat Genet (2021)
Reported Trait: Severe Autoimmune Diabetes OR: 1.07 [0.97, 1.19] PC1-10
PPM002369 PGS000857
(T2D_Obesity)
PSS001087|
European Ancestry|
3,930 individuals
PGP000211 |
Aly DM et al. Nat Genet (2021)
Reported Trait: Severe Insulin-Deficient Diabetes OR: 1.08 [1.01, 1.16] PC1-10
PPM002370 PGS000857
(T2D_Obesity)
PSS001088|
European Ancestry|
3,869 individuals
PGP000211 |
Aly DM et al. Nat Genet (2021)
Reported Trait: Severe Insulin-Resistant Diabetes OR: 1.13 [1.05, 1.22] PC1-10
PPM002371 PGS000857
(T2D_Obesity)
PSS001085|
European Ancestry|
4,116 individuals
PGP000211 |
Aly DM et al. Nat Genet (2021)
Reported Trait: Moderate Obesity-related Diabetes OR: 1.19 [1.11, 1.27] PC1-10
PPM002372 PGS000857
(T2D_Obesity)
PSS001084|
European Ancestry|
5,597 individuals
PGP000211 |
Aly DM et al. Nat Genet (2021)
Reported Trait: Moderate Age-Related Diabetes OR: 1.04 [0.99, 1.1] PC1-10
PPM020164 PGS000857
(T2D_Obesity)
PSS011301|
South Asian Ancestry|
1,282 individuals
PGP000525 |
Yajnik CS et al. Lancet Reg Health Southeast Asia (2023)
|Ext.
Reported Trait: Type 2 diabetes OR: 0.87 [0.77, 0.99] sex
PPM002373 PGS000858
(T2D_Proinsulin)
PSS001086|
European Ancestry|
3,194 individuals
PGP000211 |
Aly DM et al. Nat Genet (2021)
Reported Trait: Severe Autoimmune Diabetes OR: 0.94 [0.85, 1.04] PC1-10
PPM002374 PGS000858
(T2D_Proinsulin)
PSS001087|
European Ancestry|
3,930 individuals
PGP000211 |
Aly DM et al. Nat Genet (2021)
Reported Trait: Severe Insulin-Deficient Diabetes OR: 1.14 [1.06, 1.22] PC1-10
PPM002376 PGS000858
(T2D_Proinsulin)
PSS001085|
European Ancestry|
4,116 individuals
PGP000211 |
Aly DM et al. Nat Genet (2021)
Reported Trait: Moderate Obesity-related Diabetes OR: 1.06 [0.99, 1.13] PC1-10
PPM002377 PGS000858
(T2D_Proinsulin)
PSS001084|
European Ancestry|
5,597 individuals
PGP000211 |
Aly DM et al. Nat Genet (2021)
Reported Trait: Moderate Age-Related Diabetes OR: 1.1 [1.04, 1.16] PC1-10
PPM002375 PGS000858
(T2D_Proinsulin)
PSS001088|
European Ancestry|
3,869 individuals
PGP000211 |
Aly DM et al. Nat Genet (2021)
Reported Trait: Severe Insulin-Resistant Diabetes OR: 0.93 [0.87, 1.0] PC1-10
PPM020174 PGS000858
(T2D_Proinsulin)
PSS011301|
South Asian Ancestry|
1,282 individuals
PGP000525 |
Yajnik CS et al. Lancet Reg Health Southeast Asia (2023)
|Ext.
Reported Trait: Type 2 diabetes OR: 1.22 [1.03, 1.44] age, sex and BMI
PPM020202 PGS000858
(T2D_Proinsulin)
PSS011303|
South Asian Ancestry|
729 individuals
PGP000525 |
Yajnik CS et al. Lancet Reg Health Southeast Asia (2023)
|Ext.
Reported Trait: Mild obesity-related diabetes OR: 1.2 [1.03, 1.4] sex
PPM020214 PGS000858
(T2D_Proinsulin)
PSS011305|
South Asian Ancestry|
624 individuals
PGP000525 |
Yajnik CS et al. Lancet Reg Health Southeast Asia (2023)
|Ext.
Reported Trait: Mild age-related diabetes OR: 1.23 [1.01, 1.48] sex
PPM002403 PGS000864
(T2D-gPRS)
PSS001086|
European Ancestry|
3,194 individuals
PGP000211 |
Aly DM et al. Nat Genet (2021)
Reported Trait: Severe Autoimmune Diabetes OR: 1.42 [1.28, 1.58] PC1-10
PPM002404 PGS000864
(T2D-gPRS)
PSS001087|
European Ancestry|
3,930 individuals
PGP000211 |
Aly DM et al. Nat Genet (2021)
Reported Trait: Severe Insulin-Deficient Diabetes OR: 1.93 [1.79, 2.09] PC1-10
PPM002406 PGS000864
(T2D-gPRS)
PSS001085|
European Ancestry|
4,116 individuals
PGP000211 |
Aly DM et al. Nat Genet (2021)
Reported Trait: Moderate Obesity-related Diabetes OR: 2.12 [1.96, 2.29] PC1-10
PPM002407 PGS000864
(T2D-gPRS)
PSS001084|
European Ancestry|
5,597 individuals
PGP000211 |
Aly DM et al. Nat Genet (2021)
Reported Trait: Moderate Age-Related Diabetes OR: 1.59 [1.5, 1.69] PC1-10
PPM002405 PGS000864
(T2D-gPRS)
PSS001088|
European Ancestry|
3,869 individuals
PGP000211 |
Aly DM et al. Nat Genet (2021)
Reported Trait: Severe Insulin-Resistant Diabetes OR: 1.56 [1.45, 1.69] PC1-10
PPM021459 PGS000864
(T2D-gPRS)
PSS011738|
European Ancestry|
38,941 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Incident type 2 diabetes HR: 1.32 [1.27, 1.38] C-index: 0.731 [0.714, 0.749] Age at baseline, sex (PGS adjusted for 20 PCs prior to model fitting)
PPM021509 PGS000864
(T2D-gPRS)
PSS011736|
Hispanic or Latin American Ancestry|
33,652 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Type 2 diabetes OR: 1.02 [0.99, 1.06] AUROC: 0.745 [0.738, 0.752] Age at baseline, sex (PGS adjusted for 20 PCs prior to model fitting)
PPM021529 PGS000864
(T2D-gPRS)
PSS011740|
East Asian Ancestry|
1,149 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Incident type 2 diabetes OR: 1.04 [0.9, 1.21] AUROC: 0.584 [0.54, 0.628] Age at baseline, sex (PGS adjusted for 20 PCs prior to model fitting)
PPM021551 PGS000864
(T2D-gPRS)
PSS011741|
South Asian Ancestry|
852 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Incident type 2 diabetes OR: 1.09 [0.93, 1.28] AUROC: 0.643 [0.6, 0.686] Age at baseline, sex (PGS adjusted for 20 PCs prior to model fitting)
PPM021575 PGS000864
(T2D-gPRS)
PSS011739|
Additional Asian Ancestries|
870 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Incident type 2 diabetes OR: 0.98 [0.83, 1.16] AUROC: 0.653 [0.609, 0.697] Age at baseline, sex (PGS adjusted for 20 PCs prior to model fitting)
PPM021596 PGS000864
(T2D-gPRS)
PSS011743|
African Ancestry|
6,871 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Type 2 diabetes OR: 1.08 [1.0, 1.17] AUROC: 0.705 [0.686, 0.724] Age at baseline, sex assessment centre (PGS adjusted for 20 PCs prior to model fitting)
PPM021617 PGS000864
(T2D-gPRS)
PSS011745|
East Asian Ancestry|
1,432 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Type 2 diabetes OR: 1.05 [0.83, 1.32] AUROC: 0.7 [0.643, 0.757] Age at baseline, sex assessment centre (PGS adjusted for 20 PCs prior to model fitting)
PPM021638 PGS000864
(T2D-gPRS)
PSS011749|
South Asian Ancestry|
6,992 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Type 2 diabetes OR: 1.23 [1.16, 1.31] AUROC: 0.693 [0.678, 0.709] Age at baseline, sex assessment centre (PGS adjusted for 20 PCs prior to model fitting)
PPM021659 PGS000864
(T2D-gPRS)
PSS011742|
African Ancestry|
6,019 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Incident type 2 diabetes HR: 0.94 [0.85, 1.03] C-index: 0.639 [0.612, 0.667] Age at baseline, sex assessment centre (PGS adjusted for 20 PCs prior to model fitting)
PPM021701 PGS000864
(T2D-gPRS)
PSS011748|
South Asian Ancestry|
5,685 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Incident type 2 diabetes HR: 1.1 [1.02, 1.2] C-index: 0.604 [0.58, 0.627] Age at baseline, sex assessment centre (PGS adjusted for 20 PCs prior to model fitting)
PPM021431 PGS000864
(T2D-gPRS)
PSS011737|
European Ancestry|
109,021 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Type 2 diabetes OR: 1.34 [1.32, 1.37] AUROC: 0.687 [0.682, 0.692] Age at baseline, sex (PGS adjusted for 20 PCs prior to model fitting)
PPM021487 PGS000864
(T2D-gPRS)
PSS011735|
African Ancestry|
44,346 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Type 2 diabetes OR: 1.03 [1.0, 1.06] AUROC: 0.711 [0.705, 0.718] Age at baseline, sex (PGS adjusted for 20 PCs prior to model fitting)
PPM021680 PGS000864
(T2D-gPRS)
PSS011744|
East Asian Ancestry|
1,350 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Incident type 2 diabetes HR: 1.1 [0.81, 1.5] C-index: 0.677 [0.604, 0.75] Age at baseline, sex assessment centre (PGS adjusted for 20 PCs prior to model fitting)
PPM002413 PGS000868
(T2D_221)
PSS001092|
Ancestry Not Reported|
5,740 individuals
PGP000214 |
Aksit MA et al. J Clin Endocrinol Metab (2020)
Reported Trait: Cystic-fibrosis related diabetes HR: 1.285 PCs(1-4), site of recruitment
PPM021429 PGS000868
(T2D_221)
PSS011737|
European Ancestry|
109,021 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Type 2 diabetes OR: 1.48 [1.45, 1.51] AUROC: 0.696 [0.691, 0.701] Age at baseline, sex (PGS adjusted for 20 PCs prior to model fitting)
PPM021456 PGS000868
(T2D_221)
PSS011738|
European Ancestry|
38,941 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Incident type 2 diabetes HR: 1.6 [1.48, 1.72] C-index: 0.736 [0.719, 0.753] Age at baseline, sex (PGS adjusted for 20 PCs prior to model fitting)
PPM021483 PGS000868
(T2D_221)
PSS011735|
African Ancestry|
44,346 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Type 2 diabetes OR: 1.21 [1.17, 1.24] AUROC: 0.717 [0.711, 0.724] Age at baseline, sex (PGS adjusted for 20 PCs prior to model fitting)
PPM021507 PGS000868
(T2D_221)
PSS011736|
Hispanic or Latin American Ancestry|
33,652 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Type 2 diabetes OR: 1.38 [1.33, 1.43] AUROC: 0.758 [0.751, 0.765] Age at baseline, sex (PGS adjusted for 20 PCs prior to model fitting)
PPM021523 PGS000868
(T2D_221)
PSS011740|
East Asian Ancestry|
1,149 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Incident type 2 diabetes OR: 1.24 [1.06, 1.44] AUROC: 0.604 [0.564, 0.645] Age at baseline, sex (PGS adjusted for 20 PCs prior to model fitting)
PPM021536 PGS000868
(T2D_221)
PSS011741|
South Asian Ancestry|
852 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Incident type 2 diabetes OR: 1.52 [1.28, 1.8] AUROC: 0.677 [0.635, 0.72] Age at baseline, sex (PGS adjusted for 20 PCs prior to model fitting)
PPM021568 PGS000868
(T2D_221)
PSS011739|
Additional Asian Ancestries|
870 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Incident type 2 diabetes OR: 1.34 [1.14, 1.6] AUROC: 0.674 [0.631, 0.717] Age at baseline, sex (PGS adjusted for 20 PCs prior to model fitting)
PPM021594 PGS000868
(T2D_221)
PSS011743|
African Ancestry|
6,871 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Type 2 diabetes OR: 1.19 [1.1, 1.29] AUROC: 0.708 [0.689, 0.728] Age at baseline, sex assessment centre (PGS adjusted for 20 PCs prior to model fitting)
PPM021608 PGS000868
(T2D_221)
PSS011745|
East Asian Ancestry|
1,432 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Type 2 diabetes OR: 1.57 [1.24, 2.0] AUROC: 0.727 [0.672, 0.782] Age at baseline, sex assessment centre (PGS adjusted for 20 PCs prior to model fitting)
PPM021636 PGS000868
(T2D_221)
PSS011749|
South Asian Ancestry|
6,992 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Type 2 diabetes OR: 1.49 [1.39, 1.59] AUROC: 0.711 [0.696, 0.726] Age at baseline, sex assessment centre (PGS adjusted for 20 PCs prior to model fitting)
PPM021647 PGS000868
(T2D_221)
PSS011742|
African Ancestry|
6,019 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Incident type 2 diabetes HR: 1.13 [1.02, 1.24] C-index: 0.644 [0.616, 0.671] Age at baseline, sex assessment centre (PGS adjusted for 20 PCs prior to model fitting)
PPM021670 PGS000868
(T2D_221)
PSS011744|
East Asian Ancestry|
1,350 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Incident type 2 diabetes HR: 1.37 [0.99, 1.9] C-index: 0.684 [0.609, 0.758] Age at baseline, sex assessment centre (PGS adjusted for 20 PCs prior to model fitting)
PPM021692 PGS000868
(T2D_221)
PSS011748|
South Asian Ancestry|
5,685 individuals
PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Ext.|Pre
Reported Trait: Incident type 2 diabetes HR: 1.24 [1.14, 1.35] C-index: 0.613 [0.59, 0.637] Age at baseline, sex assessment centre (PGS adjusted for 20 PCs prior to model fitting)
PPM002414 PGS000869
(T1D_48)
PSS001092|
Ancestry Not Reported|
5,740 individuals
PGP000214 |
Aksit MA et al. J Clin Endocrinol Metab (2020)
Reported Trait: Cystic-fibrosis related diabetes HR: 1.077 PCs(1-4), site of recruitment
PPM008968 PGS001294
(GBE_HC649)
PSS004575|
African Ancestry|
6,497 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: TTE non-insulin-dependent diabetes mellitus AUROC: 0.70052 [0.68094, 0.7201] : 0.10493
Incremental AUROC (full-covars): 0.00213
PGS R2 (no covariates): 0.00615
PGS AUROC (no covariates): 0.54526 [0.52378, 0.56673]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008969 PGS001294
(GBE_HC649)
PSS004576|
East Asian Ancestry|
1,704 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: TTE non-insulin-dependent diabetes mellitus AUROC: 0.75536 [0.71488, 0.79584] : 0.1242
Incremental AUROC (full-covars): 0.01544
PGS R2 (no covariates): 0.01604
PGS AUROC (no covariates): 0.5808 [0.52621, 0.63538]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008970 PGS001294
(GBE_HC649)
PSS004577|
European Ancestry|
24,905 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: TTE non-insulin-dependent diabetes mellitus AUROC: 0.72888 [0.71557, 0.7422] : 0.10344
Incremental AUROC (full-covars): 0.03534
PGS R2 (no covariates): 0.03413
PGS AUROC (no covariates): 0.63582 [0.62119, 0.65045]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008971 PGS001294
(GBE_HC649)
PSS004578|
South Asian Ancestry|
7,831 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: TTE non-insulin-dependent diabetes mellitus AUROC: 0.68707 [0.67293, 0.70121] : 0.11343
Incremental AUROC (full-covars): 0.01724
PGS R2 (no covariates): 0.02384
PGS AUROC (no covariates): 0.58532 [0.56986, 0.60078]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008972 PGS001294
(GBE_HC649)
PSS004579|
European Ancestry|
67,425 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: TTE non-insulin-dependent diabetes mellitus AUROC: 0.71038 [0.70256, 0.71821] : 0.08854
Incremental AUROC (full-covars): 0.04133
PGS R2 (no covariates): 0.03493
PGS AUROC (no covariates): 0.63323 [0.62453, 0.64194]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008973 PGS001295
(GBE_HC165)
PSS004312|
African Ancestry|
6,497 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Type 2 diabetes AUROC: 0.68145 [0.62426, 0.73864] : 0.04466
Incremental AUROC (full-covars): 0.00427
PGS R2 (no covariates): 0.00162
PGS AUROC (no covariates): 0.5359 [0.47698, 0.59482]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008974 PGS001295
(GBE_HC165)
PSS004313|
East Asian Ancestry|
1,704 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Type 2 diabetes AUROC: 0.83509 [0.71831, 0.95186] : 0.20575
Incremental AUROC (full-covars): -0.00085
PGS R2 (no covariates): 0.00265
PGS AUROC (no covariates): 0.56328 [0.47919, 0.64736]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008975 PGS001295
(GBE_HC165)
PSS004314|
European Ancestry|
24,905 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Type 2 diabetes AUROC: 0.69318 [0.65625, 0.73011] : 0.04603
Incremental AUROC (full-covars): 0.0115
PGS R2 (no covariates): 0.00675
PGS AUROC (no covariates): 0.58258 [0.54116, 0.62401]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008976 PGS001295
(GBE_HC165)
PSS004315|
South Asian Ancestry|
7,831 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Type 2 diabetes AUROC: 0.65806 [0.61856, 0.69756] : 0.0392
Incremental AUROC (full-covars): 0.01243
PGS R2 (no covariates): 0.00618
PGS AUROC (no covariates): 0.5613 [0.5184, 0.60421]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008977 PGS001295
(GBE_H