Polygenic Scores (PGS)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS005379
(Overall_Prop_M2)
 PGP000774 |
Li JL et al. Nat Genet (2026)
 Breast cancer breast carcinoma 175,173
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005379/ScoringFiles/PGS005379.txt.gz
PGS005380
(Erpos_M1)
 PGP000774 |
Li JL et al. Nat Genet (2026)
 Estrogen-receptor positive breast cancer estrogen-receptor positive breast cancer 592,247
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005380/ScoringFiles/PGS005380.txt.gz
PGS005381
(Erpos_M2)
 PGP000774 |
Li JL et al. Nat Genet (2026)
 Estrogen-receptor positive breast cancer estrogen-receptor positive breast cancer 109,933
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005381/ScoringFiles/PGS005381.txt.gz
PGS005382
(Erneg_M1)
 PGP000774 |
Li JL et al. Nat Genet (2026)
 Estrogen-receptor negative breast cancer estrogen-receptor negative breast cancer 2,005,141
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005382/ScoringFiles/PGS005382.txt.gz
PGS005383
(Erneg_M2)
 PGP000774 |
Li JL et al. Nat Genet (2026)
 Estrogen-receptor negative breast cancer estrogen-receptor negative breast cancer 37,783
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005383/ScoringFiles/PGS005383.txt.gz
PGS005384
(TNBC_M1)
 PGP000774 |
Li JL et al. Nat Genet (2026)
 Triple-negative breast cancer triple-negative breast carcinoma 554,959
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005384/ScoringFiles/PGS005384.txt.gz
PGS005385
(TNBC_M2)
 PGP000774 |
Li JL et al. Nat Genet (2026)
 Triple-negative breast cancer triple-negative breast carcinoma 37,226
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005385/ScoringFiles/PGS005385.txt.gz
PGS005386
(TNBC_162_M1)
 PGP000774 |
Li JL et al. Nat Genet (2026)
 Triple-negative breast cancer triple-negative breast carcinoma 162
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005386/ScoringFiles/PGS005386.txt.gz
PGS005387
(TNBC_162_M2)
 PGP000774 |
Li JL et al. Nat Genet (2026)
 Triple-negative breast cancer triple-negative breast carcinoma 162
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005387/ScoringFiles/PGS005387.txt.gz
PGS005388
(PAF_PRS)
 PGP000775 |
Shiomi M et al. PLoS One (2026)
 Paroxysmal atrial fibrillation Paroxysmal atrial fibrillation 122
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005388/ScoringFiles/PGS005388.txt.gz
PGS005389
(ADRD_consensus_main_score)
 PGP000776 |
EADB et al. Nat Genet (2026)
 Alzheimer's disease Alzheimer disease 115
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005389/ScoringFiles/PGS005389.txt.gz
PGS005390
(ADRD_consensus_no_proxy_score)
 PGP000776 |
EADB et al. Nat Genet (2026)
 Alzheimer's disease Alzheimer disease 91
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005390/ScoringFiles/PGS005390.txt.gz
PGS005391
(ADRD_consensus_no_biobank_score)
 PGP000776 |
EADB et al. Nat Genet (2026)
 Alzheimer's disease Alzheimer disease 65
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005391/ScoringFiles/PGS005391.txt.gz
PGS005392
(Q-PGS4_r0.2_p5e4)
 PGP000777 |
Aliyu U et al. Front Endocrinol (Lausanne) (2024)
 HOMA2-IR HOMA-IR 1,414
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005392/ScoringFiles/PGS005392.txt.gz
PGS005393
(PGS_SEXUAL_ASSAULT_PTSD)
 PGP000778 |
Bugiga AVG et al. Braz J Psychiatry (2024)
 Post-traumatic stress disorder post-traumatic stress disorder 53,705
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005393/ScoringFiles/PGS005393.txt.gz
PGS005394
(AFR_CRC_PRS_CSx)
 PGP000779 |
David E et al. medRxiv (2026)
|Pre		 Colorectal carcinoma colorectal carcinoma 139,710
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005394/ScoringFiles/PGS005394.txt.gz
PGS005395
(AFR_PCa_PRS_CSx)
 PGP000779 |
David E et al. medRxiv (2026)
|Pre		 Prostate carcinoma prostate carcinoma 138,272
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005395/ScoringFiles/PGS005395.txt.gz
PGS005396
(AFR_BCa_PRS_CSx)
 PGP000779 |
David E et al. medRxiv (2026)
|Pre		 Breast carcinoma breast carcinoma 139,306
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005396/ScoringFiles/PGS005396.txt.gz
PGS005397
(Genome_wide_PRS)
 PGP000780 |
Boumtje V et al. Transl Oncol (2026)
 Lung cancer lung cancer 1,022,277
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005397/ScoringFiles/PGS005397.txt.gz
PGS005398
(T1D_PRS_combined)
 PGP000781 |
Qu HQ et al. Diabetes Res Clin Pract (2026)
 Type 1 diabetes (T1D) type 1 diabetes mellitus 645,391
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005398/ScoringFiles/PGS005398.txt.gz
PGS005399
(T1D_PRS_male)
 PGP000781 |
Qu HQ et al. Diabetes Res Clin Pract (2026)
 Type 1 diabetes (T1D) type 1 diabetes mellitus 264,227
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005399/ScoringFiles/PGS005399.txt.gz
PGS005400
(T1D_PRS_female)
 PGP000781 |
Qu HQ et al. Diabetes Res Clin Pract (2026)
 Type 1 diabetes (T1D) type 1 diabetes mellitus 128,279
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005400/ScoringFiles/PGS005400.txt.gz
PGS005402
(PRS121)
 PGP000783 |
Chen H et al. Genome Med (2026)
 Colorectal cancer colorectal cancer 121
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005402/ScoringFiles/PGS005402.txt.gz
PGS012513
(eoe)
 PGP000785 |
Trimarchi MP et al. J Allergy Clin Immunol (2026)
 Eosinophilic esophagitis (EOE) eosinophilic esophagitis 1,039,900
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS012513/ScoringFiles/PGS012513.txt.gz
PGS012514
(SBP)
 PGP000786 |
Huang YJ et al. Nat Commun (2026)
 Systolic blood pressure systolic blood pressure 107
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS012514/ScoringFiles/PGS012514.txt.gz
PGS012515
(DBP)
 PGP000786 |
Huang YJ et al. Nat Commun (2026)
 Diastolic blood pressure diastolic blood pressure 98
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS012515/ScoringFiles/PGS012515.txt.gz
PGS012516
(HDL)
 PGP000786 |
Huang YJ et al. Nat Commun (2026)
 HDL cholesterol high density lipoprotein cholesterol measurement 482
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS012516/ScoringFiles/PGS012516.txt.gz
PGS012517
(LDL)
 PGP000786 |
Huang YJ et al. Nat Commun (2026)
 LDL cholesterol low density lipoprotein cholesterol measurement 245
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS012517/ScoringFiles/PGS012517.txt.gz
PGS012518
(BMI)
 PGP000786 |
Huang YJ et al. Nat Commun (2026)
 Body mass index (BMI) body mass index 1,440
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS012518/ScoringFiles/PGS012518.txt.gz
PGS012519
(VTE)
 PGP000786 |
Huang YJ et al. Nat Commun (2026)
 Venous thromboembolism venous thromboembolism 46
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS012519/ScoringFiles/PGS012519.txt.gz
PGS012520
(OSA_bmi_unadj)
 PGP000786 |
Huang YJ et al. Nat Commun (2026)
 Obstructive sleep apnea obstructive sleep apnea syndrome 17
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS012520/ScoringFiles/PGS012520.txt.gz
PGS012521
(OSA_bmi_adj)
 PGP000786 |
Huang YJ et al. Nat Commun (2026)
 Obstructive sleep apnea (adjusted for BMI) obstructive sleep apnea syndrome 6
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS012521/ScoringFiles/PGS012521.txt.gz
PGS012522
(SBP_LD)
 PGP000786 |
Huang YJ et al. Nat Commun (2026)
 Systolic blood pressure systolic blood pressure 574,384
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS012522/ScoringFiles/PGS012522.txt.gz
PGS012523
(DBP_LD)
 PGP000786 |
Huang YJ et al. Nat Commun (2026)
 Diastolic blood pressure diastolic blood pressure 574,294
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS012523/ScoringFiles/PGS012523.txt.gz
PGS012524
(HDL_LD)
 PGP000786 |
Huang YJ et al. Nat Commun (2026)
 HDL cholesterol high density lipoprotein cholesterol measurement 524,956
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS012524/ScoringFiles/PGS012524.txt.gz
PGS012525
(LDL_LD)
 PGP000786 |
Huang YJ et al. Nat Commun (2026)
 LDL cholesterol low density lipoprotein cholesterol measurement 521,113
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS012525/ScoringFiles/PGS012525.txt.gz
PGS012526
(BMI_LD)
 PGP000786 |
Huang YJ et al. Nat Commun (2026)
 Body mass index (BMI) body mass index 434,712
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS012526/ScoringFiles/PGS012526.txt.gz
PGS012527
(VTE_LD)
 PGP000786 |
Huang YJ et al. Nat Commun (2026)
 Venous thromboembolism venous thromboembolism 516,802
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS012527/ScoringFiles/PGS012527.txt.gz
PGS012528
(OSA_bmi_unadj_LD)
 PGP000786 |
Huang YJ et al. Nat Commun (2026)
 Obstructive sleep apnea obstructive sleep apnea syndrome 307,286
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS012528/ScoringFiles/PGS012528.txt.gz
PGS012529
(OSA_bmi_adj_LD)
 PGP000786 |
Huang YJ et al. Nat Commun (2026)
 Obstructive sleep apnea (adjusted for BMI) obstructive sleep apnea syndrome 323,621
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS012529/ScoringFiles/PGS012529.txt.gz
PGS012530
(PRSCAD+)
 PGP000787 |
Wang H et al. Genomics Proteomics Bioinformatics (2026)
 Coronary artery disease coronary artery disorder 1,083,724
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS012530/ScoringFiles/PGS012530.txt.gz - Check Terms/Licenses
PGS012531
(ALLmeta)
 PGP000788 |
Haydarlou P et al. Nat Commun (2026)
 Atrial fibrillation atrial fibrillation 7,356,514
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS012531/ScoringFiles/PGS012531.txt.gz
PGS012532
(Mult-t-EUR)
 PGP000788 |
Haydarlou P et al. Nat Commun (2026)
 Atrial fibrillation atrial fibrillation 7,356,472
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS012532/ScoringFiles/PGS012532.txt.gz
PGS012533
(Mult-t-AMR)
 PGP000788 |
Haydarlou P et al. Nat Commun (2026)
 Atrial fibrillation atrial fibrillation 7,356,472
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS012533/ScoringFiles/PGS012533.txt.gz
PGS012534
(Mult-t-AFR)
 PGP000788 |
Haydarlou P et al. Nat Commun (2026)
 Atrial fibrillation atrial fibrillation 7,356,472
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS012534/ScoringFiles/PGS012534.txt.gz
PGS012535
(Mult-t-SAS)
 PGP000788 |
Haydarlou P et al. Nat Commun (2026)
 Atrial fibrillation atrial fibrillation 7,356,472
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS012535/ScoringFiles/PGS012535.txt.gz
PGS012536
(Mult-t-EAS)
 PGP000788 |
Haydarlou P et al. Nat Commun (2026)
 Atrial fibrillation atrial fibrillation 7,356,461
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS012536/ScoringFiles/PGS012536.txt.gz
PGS012537
(UKB_Mult-t-AFR)
 PGP000788 |
Haydarlou P et al. Nat Commun (2026)
 Atrial fibrillation atrial fibrillation 7,356,497
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS012537/ScoringFiles/PGS012537.txt.gz
PGS012538
(UKB_Mult-t-SAS)
 PGP000788 |
Haydarlou P et al. Nat Commun (2026)
 Atrial fibrillation atrial fibrillation 7,356,497
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS012538/ScoringFiles/PGS012538.txt.gz
PGS012539
(pSSNS)
 PGP000789 |
Barry A et al. Nat Commun (2023)
 Pediatric steroid-sensitive nephrotic syndrome nephrotic syndrome 1,081,086
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS012539/ScoringFiles/PGS012539.txt.gz
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