Polygenic Scores (PGS)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
Scoring File (FTP Link)
PGS005182
(VPGS_EO)
PGP000723 |
Xiang R et al. Nat Commun (2025)
Eosinophil count variance eosinophil count 8,862,968
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005182/ScoringFiles/PGS005182.txt.gz
PGS005183
(VPGS_EO_P)
PGP000723 |
Xiang R et al. Nat Commun (2025)
Eosinophil percentage of white cells variance eosinophil percentage of leukocytes 9,498,015
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005183/ScoringFiles/PGS005183.txt.gz
PGS005184
(VPGS_LYMPH_P)
PGP000723 |
Xiang R et al. Nat Commun (2025)
Lymphocyte percentage of white cells variance lymphocyte percentage of leukocytes 9,502,358
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005184/ScoringFiles/PGS005184.txt.gz
PGS005185
(VPGS_MCHC)
PGP000723 |
Xiang R et al. Nat Commun (2025)
Mean corpuscular hemoglobin concentration variance mean corpuscular hemoglobin concentration 9,502,181
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005185/ScoringFiles/PGS005185.txt.gz
PGS005186
(VPGS_MCH)
PGP000723 |
Xiang R et al. Nat Commun (2025)
Mean corpuscular hemoglobin variance mean corpuscular hemoglobin 9,498,745
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005186/ScoringFiles/PGS005186.txt.gz
PGS005187
(VPGS_MCV)
PGP000723 |
Xiang R et al. Nat Commun (2025)
Mean corpuscular volume variance erythrocyte volume 9,500,832
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005187/ScoringFiles/PGS005187.txt.gz
PGS005188
(VPGS_MPV)
PGP000723 |
Xiang R et al. Nat Commun (2025)
Mean platelet volume variance platelet volume 9,454,052
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005188/ScoringFiles/PGS005188.txt.gz
PGS005189
(VPGS_MONO)
PGP000723 |
Xiang R et al. Nat Commun (2025)
Monocyte count variance monocyte count 9,489,073
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005189/ScoringFiles/PGS005189.txt.gz
PGS005190
(VPGS_MONO_P)
PGP000723 |
Xiang R et al. Nat Commun (2025)
Monocyte percentage of white cells variance monocyte percentage of leukocytes 9,488,343
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005190/ScoringFiles/PGS005190.txt.gz
PGS005191
(VPGS_NEUT)
PGP000723 |
Xiang R et al. Nat Commun (2025)
Neutrophil count variance neutrophil count 9,499,020
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005191/ScoringFiles/PGS005191.txt.gz
PGS005192
(VPGS_NEUT_P)
PGP000723 |
Xiang R et al. Nat Commun (2025)
Neutrophil percentage of white cells variance neutrophil percentage of leukocytes 9,499,990
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005192/ScoringFiles/PGS005192.txt.gz
PGS005193
(VPGS_PLT)
PGP000723 |
Xiang R et al. Nat Commun (2025)
Platelet count variance platelet count 9,451,248
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005193/ScoringFiles/PGS005193.txt.gz
PGS005194
(VPGS_PDW)
PGP000723 |
Xiang R et al. Nat Commun (2025)
Platelet distribution width variance platelet component distribution width 9,454,587
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005194/ScoringFiles/PGS005194.txt.gz
PGS005195
(VPGS_RBC)
PGP000723 |
Xiang R et al. Nat Commun (2025)
Red blood cell count variance erythrocyte count 9,501,618
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005195/ScoringFiles/PGS005195.txt.gz
PGS005196
(VPGS_RET_P)
PGP000723 |
Xiang R et al. Nat Commun (2025)
Reticulocyte fraction of red cells variance reticulocyte amount 9,470,586
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005196/ScoringFiles/PGS005196.txt.gz
PGS005197
(VPGS_WBC)
PGP000723 |
Xiang R et al. Nat Commun (2025)
White blood cell count variance leukocyte quantity 9,503,677
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005197/ScoringFiles/PGS005197.txt.gz
PGS005198
(GIANT_BMI_2025_PRSCS)
PGP000724 |
Smit RAJ et al. Nat Med (2025)
Body mass index (BMI) body mass index 1,217,710
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005198/ScoringFiles/PGS005198.txt.gz - Check Terms/Licenses
PGS005199
(G23_BMI_2025_PRSCSx_META)
PGP000724 |
Smit RAJ et al. Nat Med (2025)
Body mass index (BMI) body mass index 1,296,245
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005199/ScoringFiles/PGS005199.txt.gz - Check Terms/Licenses
PGS005200
(G23_BMI_2025_PRSCSx_LC_AFR)
PGP000724 |
Smit RAJ et al. Nat Med (2025)
Body mass index (BMI) body mass index 1,223,921
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005200/ScoringFiles/PGS005200.txt.gz - Check Terms/Licenses
PGS005201
(G23_BMI_2025_PRSCSx_LC_AMR)
PGP000724 |
Smit RAJ et al. Nat Med (2025)
Body mass index (BMI) body mass index 1,020,295
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005201/ScoringFiles/PGS005201.txt.gz - Check Terms/Licenses
PGS005202
(G23_BMI_2025_PRSCSx_LC_EAS)
PGP000724 |
Smit RAJ et al. Nat Med (2025)
Body mass index (BMI) body mass index 1,022,487
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005202/ScoringFiles/PGS005202.txt.gz - Check Terms/Licenses
PGS005203
(G23_BMI_2025_PRSCSx_LC_EUR)
PGP000724 |
Smit RAJ et al. Nat Med (2025)
Body mass index (BMI) body mass index 1,091,375
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005203/ScoringFiles/PGS005203.txt.gz - Check Terms/Licenses
PGS005204
(G23_BMI_2025_PRSCSx_LC_SAS)
PGP000724 |
Smit RAJ et al. Nat Med (2025)
Body mass index (BMI) body mass index 1,129,666
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005204/ScoringFiles/PGS005204.txt.gz - Check Terms/Licenses
PGS005205
(PRS130_Pca)
PGP000726 |
Benafif S et al. BJU Int (2021)
Prostate cancer prostate carcinoma 130
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005205/ScoringFiles/PGS005205.txt.gz
PGS005206
(BMD_PRS)
PGP000728 |
Prijatelj V et al. Bone (2024)
Bone mineral density bone tissue density 81
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005206/ScoringFiles/PGS005206.txt.gz
PGS005207
(BCC_PRS)
PGP000729 |
Gibson TM et al. Nat Med (2024)
Basal cell carcinoma basal cell carcinoma 29
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005207/ScoringFiles/PGS005207.txt.gz
PGS005208
(Melanoma_PRS)
PGP000729 |
Gibson TM et al. Nat Med (2024)
Melanoma melanoma 67
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005208/ScoringFiles/PGS005208.txt.gz
PGS005209
(SCC_PRS)
PGP000729 |
Gibson TM et al. Nat Med (2024)
Squamous cell carcinoma squamous cell carcinoma 20
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005209/ScoringFiles/PGS005209.txt.gz
PGS005210
(Thyroid_PRS)
PGP000729 |
Gibson TM et al. Nat Med (2024)
Thyroid cancer thyroid carcinoma 12
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005210/ScoringFiles/PGS005210.txt.gz
PGS005211
(AUDIT_C)
PGP000731 |
Deng WQ et al. Alcohol Alcohol (2024)
Alcohol use disorder (3-item consumption index) alcohol use disorder measurement 2,338,199
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005211/ScoringFiles/PGS005211.txt.gz
PGS005212
(AUDIT_P)
PGP000731 |
Deng WQ et al. Alcohol Alcohol (2024)
Alcohol use disorder (7-item problematic use index) alcohol use disorder measurement 384,933
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005212/ScoringFiles/PGS005212.txt.gz
PGS005213
(AUD)
PGP000731 |
Deng WQ et al. Alcohol Alcohol (2024)
Alcohol use disorder by DSM-V alcohol use disorder measurement 336,813
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005213/ScoringFiles/PGS005213.txt.gz
PGS005214
(PAU)
PGP000731 |
Deng WQ et al. Alcohol Alcohol (2024)
Problematic alcohol use alcohol use disorder measurement 453,914
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005214/ScoringFiles/PGS005214.txt.gz
PGS005215
(addiction_rf)
PGP000731 |
Deng WQ et al. Alcohol Alcohol (2024)
Addiction risk factors substance-related disorder 11,627
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005215/ScoringFiles/PGS005215.txt.gz
PGS005216
(drinks_per_week)
PGP000731 |
Deng WQ et al. Alcohol Alcohol (2024)
Drinks per week alcohol consumption quality 221,689
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005216/ScoringFiles/PGS005216.txt.gz
PGS005217
(PRS_PAD)
PGP000732 |
Flores AM et al. JAMA Cardiol (2025)
Peripheral artery disease peripheral arterial disease 1,296,292
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005217/ScoringFiles/PGS005217.txt.gz
PGS005219
(PRS_BMIadjOSA)
PGP000734 |
Kurniansyah N et al. EBioMedicine (2025)
Obstructive sleep apnea (AdjustedBMI) obstructive sleep apnea 982,740
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005219/ScoringFiles/PGS005219.txt.gz
PGS005220
(PRS_BMIunadjOSA)
PGP000734 |
Kurniansyah N et al. EBioMedicine (2025)
Obstructive sleep apnea (UnadjustedBMI) obstructive sleep apnea 984,184
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005220/ScoringFiles/PGS005220.txt.gz
PGS005221
(General_Frailty)
PGP000735 |
Foote IF et al. Nat Genet (2024)
General factor of frailty frailty measurement 943,126
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005221/ScoringFiles/PGS005221.txt.gz
PGS005222
(F1_Frailty)
PGP000735 |
Foote IF et al. Nat Genet (2024)
Factor 1 (social isolation) of frailty frailty measurement 1,727,299
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005222/ScoringFiles/PGS005222.txt.gz
PGS005223
(F2_Frailty)
PGP000735 |
Foote IF et al. Nat Genet (2024)
Factor 2 (unhealthy lifestyle) of frailty frailty measurement 1,719,220
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005223/ScoringFiles/PGS005223.txt.gz
PGS005224
(F3_Frailty)
PGP000735 |
Foote IF et al. Nat Genet (2024)
Factor 3 (multimorbidity) of frailty frailty measurement 1,588,232
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005224/ScoringFiles/PGS005224.txt.gz
PGS005225
(F4_Frailty)
PGP000735 |
Foote IF et al. Nat Genet (2024)
Factor 4 (metabolic/respiratory problems) of frailty frailty measurement 710,413
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005225/ScoringFiles/PGS005225.txt.gz
PGS005226
(F5_Frailty)
PGP000735 |
Foote IF et al. Nat Genet (2024)
Factor 5 (poorer cognition) of frailty frailty measurement 1,715,891
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005226/ScoringFiles/PGS005226.txt.gz
PGS005227
(F6_Frailty)
PGP000735 |
Foote IF et al. Nat Genet (2024)
Factor 6 (disability) of frailty frailty measurement 1,726,064
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005227/ScoringFiles/PGS005227.txt.gz
PGS005228
(FI_Frailty)
PGP000735 |
Foote IF et al. Nat Genet (2024)
Frailty Index frailty measurement 2,379,429
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005228/ScoringFiles/PGS005228.txt.gz
PGS005229
(FFS_Frailty)
PGP000735 |
Foote IF et al. Nat Genet (2024)
Fried Frailty Score frailty measurement 2,761,868
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005229/ScoringFiles/PGS005229.txt.gz
PGS005230
(PRS71_STROKE)
PGP000736 |
Ma Y et al. Stroke (2023)
Stroke stroke 71
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005230/ScoringFiles/PGS005230.txt.gz
PGS005231
(GRS142_CAD)
PGP000738 |
Severance LM et al. JACC Cardiovasc Imaging (2021)
Coronary artery disease coronary artery disease 142
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005231/ScoringFiles/PGS005231.txt.gz
PGS005236
(CAD_AnnoPred)
PGP000740 |
Hu J et al. PLoS Comput Biol (2025)
Coronary artery disease coronary artery disease 2,994,055
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005236/ScoringFiles/PGS005236.txt.gz